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首页> 外文期刊>Indian Journal of Critical Care Medicine >Nosocomial infections in the intensive care unit: Incidence, risk factors, outcome and associated pathogens in a public tertiary teaching hospital of Eastern India
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Nosocomial infections in the intensive care unit: Incidence, risk factors, outcome and associated pathogens in a public tertiary teaching hospital of Eastern India

机译:重症监护病房的医院感染:印度东部一家公立第三级教学医院的发病率,危险因素,结果和相关病原体

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Background: The increased morbidity and mortality associated with nosocomial infections in the intensive care unit (ICU) is a matter of serious concern today. Aims: To determine the incidence of nosocomial infections acquired in the ICU, their risk factors, the causative pathogens and the outcome in a tertiary care teaching hospital. Materials and Methods: This was a prospective observational study conducted in a 12 bedded combined medical and surgical ICU of a medical college hospital. The study group comprised 242 patients admitted for more than 48 h in the ICU. Data were collected regarding severity of the illness, primary reason for ICU admission, presence of risk factors, presence of infection, infecting agent, length of ICU and hospital stay, and survival status and logistic regression analysis was done. Results: The nosocomial infection rate was 11.98% (95% confidence interval 7.89-16.07%). Pneumonia was the most frequently detected infection (62.07%), followed by urinary tract infections and central venous catheter associated bloodstream infections. Prior antimicrobial therapy, urinary catheterization and length of ICU stay were found to be statistically significant risk factors associated with nosocomial infection. Nosocomial infection resulted in a statistically significant increase in length of ICU and hospital stay, but not in mortality. Conclusion: Nosocomial infections increase morbidity of hospitalized patients. These findings can be utilized for planning nosocomial infection surveillance program in our setting.
机译:背景:重症监护病房(ICU)中与医院感染有关的发病率和死亡率增加是当今引起严重关注的问题。目的:确定三级教学医院中在ICU中获得的医院感染的发生率,其危险因素,病原体和结果。材料和方法:这是在医学院校医院的12床医疗和外科ICU中进行的前瞻性观察研究。研究组包括242名在ICU住院超过48小时的患者。收集有关疾病的严重程度,入院加护病房的主要原因,是否存在危险因素,是否存在感染,感染因素,加护病房的长短和住院时间以及生存状态和逻辑回归分析的数据。结果:医院感染率为11.98%(95%置信区间为7.89-16.07%)。肺炎是最常见的感染(62.07%),其次是尿路感染和中心静脉导管相关的血流感染。先前的抗微生物治疗,尿道插管和ICU停留时间被发现是与医院感染相关的统计学上显着的危险因素。医院内感染导致ICU长度和住院时间的统计显着增加,但死亡率没有增加。结论:医院感染增加了住院病人的发病率。这些发现可用于在我们的环境中规划医院感染监测计划。

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