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首页> 外文期刊>Indian heart journal >Assessment of periodontitis and its role in viridans streptococcal bacteremia and infective endocarditis
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Assessment of periodontitis and its role in viridans streptococcal bacteremia and infective endocarditis

机译:评估牙周炎及其在绿藻链球菌菌血症和感染性心内膜炎中的作用

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Objectives To evaluate the role of periodontitis in viridans group streptococci (VGS) bacteremia and infective endocarditis (IE). Methods A total of 200 subjects including two groups. Group A- 34 subjects undergoing tooth extraction with periodontitis, 46 subjects undergoing tooth extraction without periodontitis and 40 healthy controls. Group B: 40 confirmed cases of IE (17 with and 23 without periodontitis) and 40 healthy controls. Subgingival plaque and blood samples were obtained and processed by standard procedures. Results A total of 53 blood samples (66.25%) yielded positive cultures after tooth extraction. The relationship between the presence of periodontitis and a positive blood culture was significantly higher (p ? = ? 0.05) for tooth extraction cases with periodontitis (79.40%) than tooth extraction cases without periodontitis (56.50%). Periodontitis was observed in 42.5% of IE cases. Out of the 40 patients of IE, the blood samples yielded 40 different isolates, majority were viridans streptococci 15 (37.5%) and staphylococci nine (22.5%). No statistically significant difference was observed between the subgingival plaque and blood isolates of periodontitis in both the groups, indicating similarity of biotypes of viridans streptococci isolated from the blood and the subgingival plaque. Similarity was also observed between the antibiogram profiles of viridans streptococci from both the groups. Conclusions Periodontitis enhances viridans streptococcal bacteremia and may be a potential risk factor for IE.
机译:目的评估牙周炎在vi虫类链球菌(VGS)菌血症和感染性心内膜炎(IE)中的作用。方法共有200名受试者,包括两组。 A组-34名患有牙周炎的拔牙受试者,46名无牙周炎的拔牙受试者和40名健康对照。 B组:40例确诊的IE(17例有23例没有牙周炎)和40例健康对照。获得牙龈下斑块和血液样品,并通过标准程序进行处理。结果拔牙后共有53份血样(66.25%)产生了阳性培养物。有牙周炎的拔牙病例(79.40%)的牙周炎的存在与血液培养阳性之间的关系显着高于无牙周炎的拔牙病例(56.50%)(p = 0.05)。在IE病例中有42.5%观察到牙周炎。在40例IE病人中,血样产生了40种不同的分离株,其中多数为绿rid链球菌15株(37.5%)和葡萄球菌9株(22.5%)。两组牙龈下斑块和血液分离的牙周炎之间均未观察到统计学显着差异,表明从血液和牙龈下斑块分离出的绿箭毒链球菌的生物型相似。两组的绿色链霉菌链球菌的抗菌谱之间也观察到相似性。结论牙周炎可增强绿藻的链球菌菌血症,可能是IE的潜在危险因素。

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