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A study of correlation of red cell distribution width with the severity of coronary artery disease

机译：红细胞分布宽度与冠状动脉疾病严重程度的相关性研究

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Background: Red cell distribution width (RDW) is a measure of thevariability in the size of circulating erythrocytes, commonly utilizedin the differential diagnosis of anemia. It has been shownthat RDW is closely related to the prognosis and long term adverseevents of cardiovascular diseases. The aim of the present studywas to prospectively evaluate the severity of coronary artery diseaseby angiography and RDW at Osmania General Hospital,Hyderabad.Methods: A total of 132 consecutive patients who were admittedinto cardiology department due to the presence of typical anginaand/or positive treadmill test and underwent coronary angiographywere enrolled in the study .Based on the results of thecoronary angiography the patients were divided into two groups,CAD group (n?105) and control group (n?27).The severity of CADin each patient after angiography was evaluated by ModifiedGensini score, and its relationship with RDW was analyzed.Results: On analysis, the mean age of patients with CAD was51.74±11.20yrs and in controls was 48.22 ± 9.51 yrs. Male :Femaleratio was 3.03:1 (n?79,n?26).In patients with CAD smokersconstituted about 53.3%(n?56),diabetics were about32.3%(n?34),those with hypertension were 68.57%(n?72).family h/o CAD was seen in 21%(n?23).In patients with CAD, mean Hb was13.4±1.4,mean RDW was 16.62±1.47 where as in controls the meanHb was 13.1±1.2,mean RDW was 14.37±1.55.There was significantcorrelation of RDW in patients with high Gensini score( >13) byANOVA analysis (p?0.05). RDW correlated with severity of CADwhen the Gensini score was >6.Conclusion: RDW is associated with both presence of CAD andseverity of coronary stenosis. It can be a readily available,economical marker for the prediction of CAD. A High RDW predictsa significantly severe CAD on angiography.
机译：背景：红细胞分布宽度（RDW）是循环血红细胞大小变异性的一种量度，通常用于贫血的鉴别诊断。研究表明，RDW与心血管疾病的预后和长期不良事件密切相关。本研究的目的是通过在海得拉巴奥斯曼尼亚总医院的血管造影和RDW来前瞻性评估冠状动脉疾病的严重性。方法：总共132例因典型心绞痛和/或跑步机试验阳性而入院的连续患者根据冠状动脉造影的结果将患者分为两组，CAD组（105例）和对照组（27例）。评估了每个患者在血管造影后的CAD严重程度结果：经分析，CAD患者的平均年龄为51.74±11.20岁，对照组为48.22±9.51岁。男性：女性比率为3.03：1（n？79，n？26）。CAD吸烟者中约53.3％（n？56），糖尿病患者约32.3％（n？34），高血压者68.57％（n？34）。 n？72）。家庭h / o CAD占21％（n？23）.CAD患者的平均Hb为13.4±1.4，平均RDW为16.62±1.47，而在对照组中，平均Hb为13.1±1.2 ，平均RDW为14.37±1.55。通过ANOVA分析，Gensini评分高（> 13）的患者RDW有显着相关性（p？0.05）。当Gensini评分> 6时，RDW与CAD的严重程度相关。结论：RDW与CAD的存在和冠状动脉狭窄的严重程度相关。对于CAD的预测，它可以是一种容易获得的经济标记。高RDW预测在血管造影上会出现严重的CAD。

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