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首页> 外文期刊>Indian journal of surgical oncology >Complications of Axillary Lymph Node Dissection in Treatment of Early Breast Cancer: A Comparison of MRM and BCS
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Complications of Axillary Lymph Node Dissection in Treatment of Early Breast Cancer: A Comparison of MRM and BCS

机译:腋窝淋巴结清扫术治疗早期乳腺癌的并发症:MRM和BCS的比较

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ALND is part of primary management of breast cancer. In spite of complications it causes, its use in prognostication and planning adjuvant treatment in carcinoma breast is unquestioned. Prospective study was conducted on 100 patients of EBC [clinical stage I&II]. 50 underwent MRM, 50 WLE&AC. Patients were asked to rate on likert scale various symptoms on follow up. Multivariate regression analysis was carried out between pain, numbness, limitation of shoulder or arm motion, arm swelling, infection and age, BSA, clinical status of axilla, no. of LNs removed, no. of positive LNs, co-morbidities, chemotherapy, radiotherapy, hormone therapy, type of surgery. 60% patients reported one or more symptoms. Numbness, pain were reported by 39% each, arm swelling by 25%, limitation of arm movement by 16%, infection by 11%. Symptoms were mild in majority. On regression analyses numbness was associated with EBRT, co-morbidity, type of operation (p value- <0.01, <0.01, <0.05), pain had no significant association, swelling with EBRT, no. of LNs positive for metastases, co-morbidity, type of operation (p value- <0.01, <0.05, <0.05, <0.01), limitation of arm motion with no. of positive LNs (p value?
机译:ALND是乳腺癌主要治疗的一部分。尽管会引起并发症,但毫无疑问,它可用于乳腺癌的预后和计划辅助治疗。对100例EBC患者进行了前瞻性研究[临床I&II期]。 50名接受了MRM,50名WLE&AC。在随访中,要求患者根据李克特量表评估各种症状。在疼痛,麻木,肩膀或手臂运动受限,手臂肿胀,感染和年龄,BSA,腋窝临床状况,否之间进行了多元回归分析。删除的LN,没有。 LN阳性,合并症,化学疗法,放射疗法,激素疗法,手术类型。 60%的患者报告一种或多种症状。分别报告麻木,疼痛39%,手臂肿胀25%,手臂活动受限16%,感染11%。症状多数为轻度。在回归分析中,麻木与EBRT,合并症,手术类型相关(p值-<0.01,<0.01,<0.05),疼痛无明显关联,EBRT肿胀与否相关。转移阳性的LNs,合并症,手术类型(p值-<0.01,<0.05,<0.05,<0.01),手臂活动受限而没有。 LNs阳性(p值≤0.01),无感染。 LN阳性,合并症(p值<0.05,<0.05)。两组患者在报告症状方面没有统计学上的显着差异。 ALND导致大多数患者发病,但是很少有严重症状和干扰日常活动的报道。

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