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首页> 外文期刊>Indian Journal of Nuclear Medicine >Comparison of image quality of different radionuclides technetium-99m, samarium-153, and iodine-123
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Comparison of image quality of different radionuclides technetium-99m, samarium-153, and iodine-123

机译：radio 99m，sa 153和碘123不同放射性核素的图像质量比较

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Introduction: The choice of the radionuclide has a key role in nuclear medicine which appearing the lowest scatter fraction. In addition, the presence of penetrated and scattered photons from collimator in single-photon emission computed tomography images degrades resolution and contrast. Thus, image quality depends on sensitivity and resolution of the collimator–detector system. The goal of this study was to compare the image quality that can be achieved by three radionuclides: technetium-99 m (Tc-99 m), iodine-123 (I-123), and samarium-153 (Sm-153). Materials and Methods: Tc-99 m and Sm-153 were imaged with low-energy high resolution (LEHR) collimator, while I-123 was imaged with medium-energy (ME) collimator. We modeled the Siemens Symbia Medical system using Monte Carlo simulation code SIMIND. The imaging characteristics of each radionuclide were investigated by simulated data: point spread function, sensitivity (Cps/MBq) and geometric, penetration and scattering distribution. Results: Tc-99 m and Sm-153 give best and results with LEHR collimator for spatial resolution (full width at half maximum [FWHM] = 3.19 mm; full width at tenth maximum [FWTM] = 6.73 mm) and (FWHM = 3.22 mm; FWTM = 7.39 mm), respectively. Whereas, I-123 provided with ME collimator a lower resolution (FWHM = 4.89 mm; FWTM = 9.89 mm). The sensitivity recorded by Tc-99 m, Sm-153, and I-153 were (31.21 Cps/MBq), (10.16 Cps/MBq), and (51.22 Cps/MBq), respectively. Conclusion: Tc-99 m and Sm-153 give the best and generally similar imaging properties with LEHR. For I-123, the ME collimator helps lowering the influence of high-energy gamma rays.
机译：简介：放射性核素的选择在核医学中起着关键作用，而核医学的散射分数最低。另外，在单光子发射计算机断层图像中，来自准直仪的穿透和散射光子的存在会降低分辨率和对比度。因此，图像质量取决于准直仪-探测器系统的灵敏度和分辨率。这项研究的目的是比较三种放射性核素可以实现的图像质量：tech 99 m（Tc-99 m），碘123（I-123）和sa 153（Sm-153）。材料与方法：Tc-99 m和Sm-153用低能高分辨率（LEHR）准直仪成像，而I-123用中能（ME）准直仪成像。我们使用蒙特卡罗模拟代码SIMIND对Siemens Symbia Medical系统进行了建模。通过模拟数据研究了每种放射性核素的成像特性：点扩散函数，灵敏度（Cps / MBq）以及几何，穿透和散射分布。结果：Tc-99 m和Sm-153使用LEHR准直仪可获得最佳的空间分辨率结果（半高处的全宽[FWHM] = 3.19 mm;十分之一处的全宽[FWTM] = 6.73 mm）和（FWHM = 3.22毫米; FWTM = 7.39毫米）。而I-123为ME准直仪提供了较低的分辨率（FWHM = 4.89 mm; FWTM = 9.89 mm）。 Tc-99 m，Sm-153和I-153记录的灵敏度分别为（31.21 Cps / MBq），（10.16 Cps / MBq）和（51.22 Cps / MBq）。结论：Tc-99 m和Sm-153与LEHR相比具有最佳和通常相似的成像性能。对于I-123，ME准直仪有助于降低高能伽马射线的影响。

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