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首页> 外文期刊>Indian Journal of Psychological Medicine >Severe Tardive Dystonia on Low Dose Short Duration Exposure to Atypical Antipsychotics: Factors Explored
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Severe Tardive Dystonia on Low Dose Short Duration Exposure to Atypical Antipsychotics: Factors Explored

机译:低剂量短时暴露于非典型抗精神病药的严重迟发性肌张力障碍:探索因素。

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摘要

Tardive dystonia (TD) is a serious side effect of antipsychotic medications, more with typical antipsychotics, that is potentially irreversible in affected patients. Studies show that newer atypical antipsychotics have a lower risk of TD. As a result, many clinicians may have developed a false sense of security when prescribing these medications. We report a case of 20-year-old male with hyperthymic temperament and borderline intellectual functioning, who developed severe TD after low dose short duration exposure to atypical antipsychotic risperidone and then olanzapine. The goal of this paper is to alert the reader to be judicious and cautious before using casual low dose second generation antipsychotics in patient with no core psychotic features, hyperthymic temperament, or borderline intellectual functioning suggestive of organic brain damage, who are more prone to develop adverse effects such as TD and monitor the onset of TD in patients taking atypical antipsychotics.
机译:迟发性肌张力障碍(TD)是抗精神病药物的严重副作用,更多的是典型的抗精神病药物,在受影响的患者中可能是不可逆的。研究表明,较新的非典型抗精神病药具有较低的TD风险。结果,许多临床医生在开这些药物时可能会产生一种错误的安全感。我们报告了一例20岁的男性,患有高胸腺性气质和边缘性智力功能,在低剂量短时间短时间暴露于非典型抗精神病药物利培酮之后再发展为奥氮平后出现严重的TD。本文的目的是在没有核心精神病特征,高胸腺性气质或边缘性智力功能提示有机性脑损伤的患者中使用偶然的低剂量第二代抗精神病药之前,警告读者要谨慎和谨慎。服用非典型抗精神病药的患者的不良反应(如TD)并监测TD的发作。

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