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首页> 外文期刊>Annals of clinical neurophysiology. >Clinical and Electrophysiological Changes after Open Carpal Tunnel Release: Preliminary Study of 25 Hands
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Clinical and Electrophysiological Changes after Open Carpal Tunnel Release: Preliminary Study of 25 Hands

机译：腕管开放释放后的临床和电生理变化：25只手的初步研究

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Background: Electrophysiological study has been known as a useful method to evaluate the therapeutic effect of operation in idiopathic carpal tunnel syndrome (CTS). The purpose of this study was to evaluate the clinical and electrophysiological changes after carpal tunnel release (CTR) compared to the preoperative results. Methods: We analyzed the changes of nerve conduction study (NCS) before and after minimal open carpal tunnel release in 18 patients (25 hands) with CTS. Follow-up study was performed over 6 months after operation. Results: Clinical improvement was seen in all cases after CTR. In contrast, electrophysiological improvement was various depending on the parameters; the mean median sensory latency and nerve conduction velocity (NCV) improved significantly (p = 0.001). The mean median motor latency also improved, but NCV and compound muscle action potential (CMAP) amplitude did not change. The extent of improvement was evident in moderate CTS, but not in severe CTS. Conclusions: In this preliminary study, all subjects who underwent CTR achieved a clinical relief along with a significant improvement of electrophysiological parameters such as median sensory latency, sensory NCV and median distal motor latency. After CTR, a number of cases with mild to moderate CTS showed a prominent improvement of clinical and electrophysiological parameters, while fewer improvements were seen in severe CTS, although it did not reach the statistical significance.
机译：背景：电生理学研究是评估手术治疗特发性腕管综合症（CTS）疗效的有效方法。这项研究的目的是评估与手术前结果相比，腕管释放（CTR）后的临床和电生理变化。方法：我们分析了18例CTS患者（25手）在最小程度的开放腕管释放之前和之后的神经传导研究（NCS）的变化。术后6个月进行随访研究。结果：CTR后所有病例均见临床改善。相反，电生理学的改善取决于参数。平均中位感觉潜伏期和神经传导速度（NCV）显着改善（p = 0.001）。平均中位运动潜伏期也有所改善，但NCV和复合肌肉动作电位（CMAP）幅度没有变化。改善程度在中度CTS中很明显，但在重度CTS中没有。结论：在这项初步研究中，所有接受CTR的受试者均取得了临床缓解，并且电生理参数（例如中位感觉潜伏期，NCV感觉和远端运动潜伏期中位数）显着改善。 CTR后，许多轻度至中度CTS病例的临床和电生理指标均有显着改善，而严重CTS的改善较少，尽管未达到统计学意义。

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