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Relation of Bony Carotid Canal Diameter and Clinical Manifestations in Patients with Moyamoya Disease

机译:烟雾病患者的颈动脉直径与临床表现的关系

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Background: Moyamoya disease is characterized by a progressive stenosis or occlusion of the intracranial internal carotid artery and/or the proximal portion of the anterior cerebral artery and middle cerebral artery. Whether the onset time was childhood or adulthood, the bony carotid canal diameter might be different, but reflects the size of internal carotid artery passing through the bony carotid canal. In this study, we aimed to identify the relationship between bony carotid canal diameter and clinical manifestation. Methods: 146 consecutive patients diagnosed with moyamoya disease by brain imaging studies were included. We measured the diameter of a transverse portion of bony carotid canal on bone window of a brain computed tomography(CT) image. Patients were divided into two groups, ischemic or hemorrhagic stroke according to clinical manifestation. As a result, 115 patients were included. The Suzuki stage was used as criteria for disease progression. Results: Bony carotid canal diameter was 3.6 ± 0.5 (right) and 3.6 ± 0.4 (left) in the hemorrhagic stroke group, and 3.7 ± 0.4 (right) and 3.6 ± 0.4 (left) in the ischemic stroke group. The bony carotid canal diameter of the moyamoya vessels (3.6 mm) was smaller than the diameter of non-moyamoya vessels (3.8 mm), significantly (p = 0.042). However, there was no difference in the collateral patterns and clinical manifestation in a comparison of both groups. Conclusions: In our study, there was no significant difference of clinical manifestations and collateral patterns depend on the bony carotid canal diameter in patients with moyamoya disease. These findings suggest that the clinical presentations of moyamoya disease are not related to the onset time of the disease.
机译:背景:烟雾病的特征是颅内颈内动脉和/或大脑前动脉和大脑中动脉的近端逐渐狭窄或闭塞。无论发病时间是儿童时期还是成年时期,骨性颈总动脉直径可能有所不同,但反映了穿过骨性颈总动脉的颈内动脉大小。在这项研究中,我们旨在确定骨性颈动脉管直径与临床表现之间的关系。方法:纳入146例通过脑成像研究诊断为烟雾病的患者。我们在大脑计算机断层扫描(CT)图像的骨窗上测量了骨颈动脉横断部分的直径。根据临床表现将患者分为缺血性或出血性中风两组。结果,包括115名患者。铃木阶段用作疾病进展的标准。结果:出血性卒中组的颈动脉直径为3.6±0.5(右)和3.6±0.4(左),缺血性卒中组为3.7±0.4(右)和3.6±0.4(左)。 Moyamoya血管的骨颈动脉直径(3.6 mm)比非Moyamoya血管的直径(3.8 mm)小得多(p = 0.042)。然而,两组的侧支模式和临床表现没有差异。结论:在我们的研究中,烟雾病患者的临床表现无明显差异,侧支方式取决于骨颈管直径。这些发现表明,烟雾病的临床表现与疾病的发作时间无关。

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