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首页> 外文期刊>Indian Pacing and Electrophysiology Journal >Dronedarone for Recurrent Ventricular Tachycardia: A Real Alternative? >
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Dronedarone for Recurrent Ventricular Tachycardia: A Real Alternative? >

机译:使用地雷达隆治疗复发性室性心动过速:真正的选择吗? >

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摘要

Sustained ventricular tachycardia (VT) is an important cause of morbidity and sudden death in patients with dilated cardiomyopathy. Although ICD effectively terminate VT episodes and improve survival, shocks reduce quality of life, and episodes of VT predict increased risk of heart failure and death despite effective therapy. Patients suffering recurrent VT episodes remain a challenge. Antiarrhytmic therapy reduces VT episodes, but it is associated with serious adverse events, and disappointing efficacy. Catheter ablation has emerged as an important option to control recurrent VT, but major procedure-related complications, and even death, are still issues to concern. And even with these armamentaria, some patients still have recurrent VT episodes and ICD shocks. We report on a patient with non-ischemic dilated cardiomyopathy and recurrent ventricular tachycardia resistant to multiple antiarrhytmic agents, in whom dronedarone was effective in completely suppressing ventricular tachycardia episodes.
机译:持续性室性心动过速(VT)是扩张型心肌病患者发病和突然死亡的重要原因。尽管ICD有效终止了室速发作并改善了生存率,但电击降低了生活质量,尽管进行了有效的治疗,室速发作仍预示着心衰和死亡的风险增加。反复发作室速发作的患者仍然是一个挑战。抗心律失常疗法减少了室速发作,但与严重的不良事件和令人失望的疗效相关。导管消融已成为控制复发性室速的重要选择,但与手术相关的主要并发症甚至死亡仍是值得关注的问题。即使有这些军备病,一些患者仍会反复出现室速发作和ICD休克。我们报道了一名非缺血性扩张型心肌病和对多种抗心律失常药耐药的复发性室性心动过速的患者,其中决奈达隆有效地完全抑制了室性心动过速发作。

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