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首页> 外文期刊>Internal medicine. >Skin Necrosis Due to the Extravasation of Irritant Anticancer Agents
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Skin Necrosis Due to the Extravasation of Irritant Anticancer Agents

机译：由于刺激性抗癌药的外渗导致皮肤坏死

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A 70-year-old man with malignant lymphoma was subjected to a fourth course of chemotherapy using gemcitabine and cisplatin. During the intravenous infusion of anticancer agents, pain and redness was observed at the site of insertion. The patient was subsequently treated with the strongest topical steroids and topical cooling agents. However, 2 weeks later, the affected area turned yellow, and the histopathological findings revealed skin necrosis of the entire dermis layer. It took two and a half months to cure the lesion. Close attention should be paid to the development of skin necrosis even when irritant anticancer agents such as gemcitabine and cisplatin are administered.
机译：一名70岁的恶性淋巴瘤患者接受了吉西他滨和顺铂化疗的第四个疗程。在静脉内输注抗癌剂期间，在插入部位观察到疼痛和发红。随后，该患者接受了最强的局部类固醇和局部清凉剂治疗。然而，两周后，患处变成黄色，组织病理学发现显示整个真皮层皮肤坏死。治愈了两个半月。即使使用吉西他滨和顺铂等刺激性抗癌剂，也应密切注意皮肤坏死的发生。

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