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首页> 外文期刊>Internal medicine. >Importance of Vital Signs to the Early Diagnosis and Severity of Sepsis: Association between Vital Signs and Sequential Organ Failure Assessment Score in Patients with Sepsis
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Importance of Vital Signs to the Early Diagnosis and Severity of Sepsis: Association between Vital Signs and Sequential Organ Failure Assessment Score in Patients with Sepsis

机译：生命体征对脓毒症的早期诊断和严重性的重要性：脓毒症患者生命体征与顺序器官衰竭评估评分之间的关​​联

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Objective While much attention is given to the fifth vital sign, the utility of the 4 classic vital signs (blood pressure, respiratory rate, body temperature, and heart rate) has been neglected. The aim of this study was to assess a possible association between vital signs and the Sequential Organ Failure Assessment (SOFA) score in patients with sepsis. Methods We performed a prospective, observational study of 206 patients with sepsis. Blood pressure, respiratory rate, body temperature, and heart rate were measured on arrival at the hospital. The SOFA score was also determined on the day of admission. Results Bivariate correlation analysis showed that all of the vital signs were correlated with the SOFA score. Multiple regression analysis indicated that decreased values of systolic blood pressure (multivariate regression coefficient [Coef] = -0.030, 95% confidence interval [CI] = -0.046 to -0.013) and diastolic blood pressure (Coef = -0.045, 95% CI = -0.070 to -0.019), increased respiratory rate (Coef = 0.176, 95% CI = 0.112 to 0.240), and increased shock index (Coef = 4.232, 95% CI = 2.401 to 6.062) significantly influenced the SOFA score. Conclusion Increased respiratory rate and shock index were significantly correlated with disease severity in patients with sepsis. Evaluation of these signs may therefore improve early identification of severely ill patients at triage, allowing more aggressive and timely interventions to improve the prognosis of these patients.
机译：目的尽管对第五个生命体征给予了极大关注，但忽略了这四个经典生命体征（血压，呼吸频率，体温和心律）的实用性。这项研究的目的是评估脓毒症患者生命体征与序贯器官衰竭评估（SOFA）评分之间的可能关联。方法我们对206例败血症患者进行了一项前瞻性观察研究。到达医院时测量血压，呼吸频率，体温和心率。 SOFA分数也在入学当天确定。结果双变量相关分析表明，所有生命体征均与SOFA评分相关。多元回归分析表明收缩压值（多元回归系数[Coef] = -0.030，95％置信区间[CI] = -0.046至-0.013）和舒张压降低（Coef = -0.045，95％CI = -0.070至-0.019），呼吸频率增加（Coef = 0.176、95％CI = 0.112至0.240）和增加的休克指数（Coef = 4.232、95％CI = 2.401至6.062）显着影响了SOFA评分。结论败血症患者呼吸频率和休克指数的升高与疾病的严重程度密切相关。因此，对这些体征的评估可以改善对重病患者进行分诊的早期识别，从而可以采取更积极，及时的干预措施来改善这些患者的预后。

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