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首页> 外文期刊>International Journal of Basic & Clinical Pharmacology >Pattern and pharmacotherapy of acute poisonings presenting to a tertiary care centre
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Pattern and pharmacotherapy of acute poisonings presenting to a tertiary care centre

机译：出现在三级护理中心的急性中毒的模式和药物治疗

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Background: Acute poisoning, a therapeutic emergency and one of the common causes of morbidity and mortality globally. The rate of mortality in developed countries range from 1-2%, but in India it varies between 15-30%. According to World Health Organization (WHO), globally more than three million acute poisoning cases with 2,20,000 deaths occur annually. Most of the fatalities are due to the victim not reaching the hospital in time. This study aims to evaluate the pattern of acute cases of poisoning in tertiary care hospital attached to BMCRI. Methods: Prospective, observational study based on hospital records at tertiary care hospital (twelve months). Data regarding demographic profile and treatment was collected. Data was analyzed using descriptive statistics and SPSS-24. Results: Out of a total of 810 poisoning cases, 608 were included (381 poisoning, 138 drug overdose and 89 snake bite). Organophosphorus compounds (OPC) (131/608) and Aluminium phosphide (43/608) were the commonest poisons consumed in the age group 21-30 years. Sedative-hypnotics, non-benzodiazepine antiepileptics (non BZD AEDs) and paracetamol were common drug overdose cases. Snake bite accounted for 14.6%. Conclusions: OP compounds were the most common among poisons, while sedatives-hypnotics were frequently consumed drugs, followed by Snake bite. Young adults from urban areas were the common victims with suicidal intention. This reflects the need for stringent rules regarding the availability and sale of drugs and poisonous substances.
机译：背景：急性中毒，治疗上的紧急情况，是全球发病率和死亡率的常见原因之一。发达国家的死亡率为1-2％，而印度为15-30％。根据世界卫生组织（WHO）的数据，全球每年发生超过300万例急性中毒病例，其中220,000人死亡。多数死亡是由于受害者没有及时到达医院。本研究旨在评估BMCRI附属三级医院急性中毒病例的模式。方法：根据三级医院（十二个月）的医院记录进行前瞻性观察研究。收集有关人口统计资料和治疗的数据。使用描述性统计数据和SPSS-24分析数据。结果：在810例中毒病例中，包括608例（381例中毒，138剂药物过量和89例蛇咬伤）。有机磷化合物（OPC）（131/608）和磷化铝（43/608）是21至30岁年龄组中最常见的毒物。镇静催眠药，非苯二氮卓类抗癫痫药（非BZD AED）和扑热息痛是常见的药物过量病例。蛇咬占14.6％。结论：OP化合物是最常见的毒药，而镇静剂-催眠药是经常食用的药物，其次是Snake bite。来自城市地区的年轻人是有自杀意图的常见受害者。这反映出需要关于药物和有毒物质的供应和销售的严格规定。

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