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首页> 外文期刊>International Journal of Basic Medical Sciences and Pharmacy >Prevalence, Types and Predictors of Potential Drug-Drug Interactions in an Internal Medicine Ward of The Mardan Medical Complex, Mardan,Kpk, Pakistan
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Prevalence, Types and Predictors of Potential Drug-Drug Interactions in an Internal Medicine Ward of The Mardan Medical Complex, Mardan,Kpk, Pakistan

机译：巴基斯坦马尔丹马尔丹市马尔丹医疗中心内科病房内潜在药物-药物相互作用的发生率，类型和预测因子

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The aim of this study was to determine the prevalence, types and predictors of potential drug-drug interactions (pDDIs). In this retrospective study, medication records of 40 patients were randomly selected from the internal medicine ward and analyzed for pDDIs. A total of 30 interacting drug pairs resulted into 53 pDDIs. Overall 52.50% patients have at least 1 pDDI regardless of the type of severity; 12.50%, 25% and 42.50% patients have at least one major, moderate and minor pDDI. Out of 53 pDDI the basis of severity 58.49%, 26.41% and 15.41% were of minor, moderate and major types respectively; 96.30% were of delayed onset; whereas those with probable and suspected scientific evidences were 37.73% each. pDDIs were more prevalent in the internal medicine ward, majority of which were of minor type of severity. Patients prescribed with more than 7 number of medication were at high risk of occurrence of pDDIs.
机译：这项研究的目的是确定潜在药物-药物相互作用（pDDIs）的发生率，类型和预测因子。在这项回顾性研究中，从内科病房中随机选择40名患者的用药记录并分析pDDI。总共30个相互作用的药物对产生了53个pDDI。总体上52.50％的患者至少具有1 pDDI，而与严重程度类型无关; 12.50％，25％和42.50％的患者至少有一种主要，中度和次要pDDI。在53种pDDI中，严重程度分别为轻度，中度和主要类型的分别为58.49％，26.41％和15.41％; 96.30％的患者延迟发作;而那些拥有可能和怀疑的科学证据的人则为37.73％。 pDDI在内科病房中更为普遍，其中大多数是轻度的。开具7种以上药物的患者发生pDDI的风险很高。

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