• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>International Journal of Basic Medical Sciences and Pharmacy >Isolation and spectroscopy study of the psoralens from Ficus Sycomorus sap. Its thermal and kinetic effects in collagen forms
【24h】

Isolation and spectroscopy study of the psoralens from Ficus Sycomorus sap. Its thermal and kinetic effects in collagen forms

机译：榕无花果汁中补骨脂素的分离和光谱研究。它以胶原形式的热和动力学作用

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Psoralen and antioxidants were isolated for the first time from Ficus Sycomorus (FS) sap, localised in the trunk of the tree and are characterized by 1D and 2D NMR spectroscopy. The bioactive constituents of the sap were incorporated in the collagen gel, which is prepared further in membranes and matrices forms, using a methodology developed in our laboratories. Collagen gels with FS content were dried by different processes like freeze-drying and free drying at 25 oC in order to obtain matrices and membranes because they will be used as vehicles for topical systems with controlled release of bioactive components from FS. The thermal and structural changes caused by the presence of psoralens in membranes and matrices have been studied using Differential Scanning Calorimetry, UV and IR. In addition, in vitro kinetic studies revealed the possible mechanisms of the FS release and showed that FS extract has the potential to be used in these forms as a future therapeutic approach for psoriasis.
机译：补骨脂素和抗氧化剂是首次从榕树（FS）汁液中分离出来的，定位在树的树干上，并通过1D和2D NMR光谱进行了表征。使用我们实验室开发的方法，将汁液的生物活性成分掺入胶原蛋白凝胶中，胶原蛋白凝胶进一步制成膜和基质形式。具有FS含量的胶原蛋白凝胶通过冷冻干燥和在25 oC下自由干燥等不同过程进行干燥，以获得基质和膜，因为它们将用作局部系统的载体，可控制生物活性成分从FS释放。使用差示扫描量热法，紫外线和红外线研究了膜和基质中补骨脂素的存在引起的热和结构变化。此外，体外动力学研究揭示了FS释放的可能机制，并表明FS提取物有潜力以这些形式用作牛皮癣的未来治疗方法。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号