• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>International Journal of Basic & Clinical Pharmacology >Compare Brimonidine 0.2% versus Latanoprost 0.005% (Xalatan) in preventing intraocular pressure after YAG laser posterior capsulotomy in patients visiting ophthalmology clinic in Ardabil city
【24h】

Compare Brimonidine 0.2% versus Latanoprost 0.005% (Xalatan) in preventing intraocular pressure after YAG laser posterior capsulotomy in patients visiting ophthalmology clinic in Ardabil city

机译：比较在使用Ardabil市眼科门诊进行YAG激光后囊切开术后预防眼压的溴莫尼定0.2％与拉坦前列素0.005％（Xalatan）的比较

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background: The transient increase of intraocular pressure (IOP) following neodymium YAG laser capsulotomy can occur in a significant number of patients, which requires prophylactic treatment with IOP reducing drugs, and in some patients, postoperative IOP monitoring. This study was performed to compare the efficacy of brimonidine 0.2% versus latanoprost0.005% (Xalatan) in preventing the IOP elevation after YAG laser posterior capsulotomy in patients visiting ophthalmology clinic in Alavi Hospital. Methods: This study was a randomized, double-blind clinical trial that included 100 patients who had developed posterior capsule opacification (PCO) as a result of previous cataract surgery and were candidate for undergoing YAG laser posterior capsulotomy. The patients were randomly divided into two groups of 50 patients. One group received brimonidine 0.2% one hour before surgery, and the other group received Xalatan 0.005% in the night before laser surgery. In both groups the patients' IOP was measured in baseline, 1, 2, 3, 24 hours, 3 days and one week after surgery. The gathered data were analyzed using statistical methods in SPSS.16. Results: The mean IOP, 1, 2, 3, and 24 hours, 3 days, and one week after surgery didn't show any significant difference between two groups. IOP one hour before surgery changed significantly compared to one hour after surgery and a statistically significant relationship was found between the two groups, though at other times of measurement, the differences were not significant. Conclusions: Results showed that using Brimonidine 0.2% or Latanoprost 0.005% as prophylactic before YAG laser posterior capsulotomy could be effective in preventing IOP after treatment.
机译：背景：钕YAG激光囊切开术后眼内压（IOP）的短暂升高可能发生在许多患者中，这需要使用降低IOP的药物进行预防性治疗，并且在某些患者中需要进行术后IOP监测。进行这项研究的目的是为了比较0.2％溴莫尼定和latanoprost0.005％（Xalatan）预防在Alavi医院眼科门诊进行YAG激光后囊切开术后的IOP升高的疗效。方法：该研究是一项随机，双盲临床试验，其中包括100例因先前的白内障手术而发生后囊混浊（PCO）的患者，这些患者可以接受YAG激光后囊切开术。将患者随机分为两组，每组50例。一组在手术前一小时接受溴莫尼定0.2％，另一组在激光手术前一夜接受Xalatan 0.005％。在两组中，均在手术后1、2、3、24小时，3天和1周测量患者的IOP。使用SPSS.16中的统计方法分析收集的数据。结果：两组术后1、2、3和24小时，3天和1周的平均眼压没有明显差异。与手术后一小时相比，手术前一小时的眼压发生了显着变化，两组之间存在统计学意义的相关性，尽管在其他测量时间，差异并不显着。结论：结果表明，在YAG激光后囊切开术之前使用0.2％的溴莫尼定或0.005％的拉坦前列素作为预防剂可有效预防治疗后的IOP。

著录项

相似文献

  • 外文文献
  • 中文文献
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号