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Biochemical Changes in Albino Rats Exposedto Rice Husk Dusk at Abakaliki Rice MillIndustrial Area

机译:Abakaliki稻米工业区暴露于稻壳黄昏的白化病大鼠的生化变化

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Purpose: The effect of rice husk dust inhalation on some biochemical parameters was conducted on albino rats. Method: 100 albino rats were divided into five groups with each group containing twenty albino rats. Group A served as the control and were housed at the animal house away from rice dust while group B, C, and D were exposed to rice husk dust for two week, three weeks and four weeks respectively for dust inhalation. They were allowed access to rats feeds and deionized water ad libitium. Blood samples were collected from each group at the end of exposure by cardiac puncture. Glucose level was determined using the glucose reagent kit, acid phosphatase concentration was performed using reagent kits, creatinine and uric acid concentration was determined spectrophotometrically, the weight of the rats were recorded daily. Results: Result showed significant reduction in body weight of the exposed. The glucose level decreased significantly while the serum acid phosphatase and serum uric acid level showed a significant increase. Histological result showed various degrees of damage to the kidney of the exposed rats. Conclusion: We therefore conclude that rice husk dust inhalation induces glucose depletion, injury to the kidney and prostatic glands in the albino rat and impairs the renal function.
机译:目的:对白化病大鼠进行稻壳粉尘吸入对某些生化指标的影响。方法:将100只白化病大鼠分为5组,每组20只。 A组作为对照并被安置在远离稻米粉尘的动物房中,而B,C和D组分别暴露于稻壳粉尘两周,三周和四周以吸入粉尘。允许他们随意摄取大鼠饲料和去离子水。在暴露结束时通过心脏穿刺从每组收集血样。使用葡萄糖试剂盒测定葡萄糖水平,使用试剂盒测定酸性磷酸酶浓度,通过分光光度法测定肌酐和尿酸浓度,每天记录大鼠的体重。结果:结果显示暴露的体重显着降低。葡萄糖水平显着降低,而血清酸性磷酸酶和血清尿酸水平则显着升高。组织学结果显示暴露大鼠的肾脏受到不同程度的损害。结论:因此,我们得出结论,稻壳粉尘吸入可引​​起白化病大鼠的葡萄糖耗竭,肾脏和前列腺的损害,并损害肾功能。

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