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Solitary juvenile xanthogranuloma with tibial involvement: a case report

机译:胫骨受累孤立性青少年黄肉芽肿:病例报告

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Juvenile xanthogranuloma (JXG) is a rare disease that is part of a spectrum of histiocytic dendritic cell disorders. Most patients present with a solitary cutaneous lesion; however, others present with extracutaneous manifestations or even with systemic involvement. We present the first report of an 11-month-old girl in whom was diagnosed a unifocal extracutaneous JXG involving the tibia. Histological and immunohistochemical staining results are presented. A review of the literature on these unusual lesions is conducted, along with discussion of their differential diagnosis and key aspects of the patient’s evaluation, management, and pathological diagnosis.
机译:少年黄肉芽肉瘤(JXG)是一种罕见疾病,属于组织细胞树突状细胞疾病的一部分。大多数患者出现孤立的皮肤病灶。然而,其他人表现出皮外表现,甚至全身性受累。我们提供了一个11个月大女孩的首次报告,该女孩被诊断出涉及胫骨的单焦点皮下JXG。呈现组织学和免疫组化染色结果。对这些异常病变的文献进行了综述,并讨论了它们的鉴别诊断以及患者评估,治疗和病理诊断的关键方面。

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