Recent Progress in Electrochemical Biosensors for Detection of DNA Methylation and Methyltransferase Activity

NingXia; YuanqiangHao

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Recent Progress in Electrochemical Biosensors for Detection of DNA Methylation and Methyltransferase Activity

机译：用于检测DNA甲基化和甲基转移酶活性的电化学生物传感器的最新进展

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DNA methylation is one of the most studied epigenetic modifications of DNA. The methylation at C-5position of cytosine has been proved to be related to a wide range of biological phenomena. Therefore,it is very important to develop a simple, sensitive, accurate and reliable method for DNA methylationanalysis. In this paper, the electrochemical biosensors for assays of DNA methylation andmethyltransferase activity are reviewed.

机译：DNA甲基化是对DNA进行研究最多的表观遗传修饰之一。已经证明胞嘧啶的C-5位甲基化与广泛的生物学现象有关。因此，开发一种简单，灵敏，准确，可靠的DNA甲基化分析方法非常重要。本文综述了用于测定DNA甲基化和甲基转移酶活性的电化学生物传感器。

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《International Journal of Electrochemical Science》 |2019年第2期|共12页
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NingXia; YuanqiangHao;
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1. A sensitive electrochemical biosensor for detection of DNA methyltransferase activity by combining DNA methylation-sensitive cleavage and terminal transferase-mediated extension [J] . Huiwang Wu, Shucheng Liu, Jianhui Jiang, Chemical Communications . 2012,第50期

机译：通过结合DNA甲基化敏感性切割和末端转移酶介导的延伸来检测DNA甲基转移酶活性的灵敏电化学生物传感器
2. Fluorescence biosensor for DNA methyltransferase activity and related inhibitor detection based on methylation-sensitive cleavage primer triggered hyperbranched rolling circle ampli fication [J] . Analytica chimica acta . 2020,第期

机译：用于DNA甲基转移酶活性的荧光生物传感器和相关抑制剂检测基于甲基化敏感性裂解引发的超支化滚动圆爆发
3. A dual-response biosensor for electrochemical and glucometer detection of DNA methyltransferase activity based on functionalized metal-organic framework amplification [J] . Chen Ying, Meng Xian-Zhu, Gu Hui-Wen, Biosensors & Bioelectronics: The International Journal for the Professional Involved with Research, Technology and Applications of Biosensers and Related Devices . 2019,第期

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4. DNA Methyltransferase activity detection using the personal glucose meter [C] . Huimin Deng, Si Ying Png, Zhiqiang Gao International Conference on Sensing Technology . 2015

机译：使用个人血糖仪进行DNA甲基转移酶活性检测
5. An Electrochemical DNA Biosensor for the Detection of Salmonella Using Polymeric Films and Electrochemical Labels [D] . Diaz Serrano, Madeline 2011

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6. Electrochemical Assay for the Signal-on Detection of Human DNA Methyltransferase Activity [O] . Natalie B. Muren, Jacqueline K. Barton -1

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Recent Progress in Electrochemical Biosensors for Detection of DNA Methylation and Methyltransferase Activity

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