首页> 外文期刊>International Journal of Electrochemical Science >Potentiometric Determination of Loperamide Hydrochloride by Loperamide PVC Membrane and Nano-Composite Electrodes
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Potentiometric Determination of Loperamide Hydrochloride by Loperamide PVC Membrane and Nano-Composite Electrodes

机译:洛哌丁胺PVC膜和纳米复合电极电位滴定法测定盐酸洛哌丁胺。

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In this work, two new loperamide potentiometric electrodes were prepared and used forpharmaceutical analysis. In case of liquid membrane electrode, the best results were obtained from theelectrode with the membrane composition of 5% ion-pair, 1% NaTPB, 30% PVC, and 64% DBP. The-5 proposed sensor shows a Nernstian response (slope of 57.2 mV per decade) in the range of 3.010 - 1.010-2 mol L-1. In case of carbon paste electrode modified by MWCNTs, calibration graph slope is-5 -2 about 58.5 mV per decade in the concentration range of loperamide hydrochloride 1.010 -1.010mol L-1. Both sensors work well in the laboratory conditions and successfully applied in analysis ofloperamide in some pharmaceutical formulations.
机译:在这项工作中,准备了两个新的洛哌丁胺电位电极,并将其用于药物分析。对于液膜电极,从电极组成为5%离子对,1%NaTPB,30%PVC和64%DBP的电极中可获得最佳结果。提出的-5型传感器在3.010-1.010-2 mol L-1范围内显示出能斯特响应(每十年的斜率为57.2 mV)。在用碳纳米管修饰的碳糊电极的情况下,在盐酸洛哌丁胺1.010 -1.010mol L-1的浓度范围内,校正曲线图的斜率是每十倍-5 -2约58.5 mV。两种传感器在实验室条件下均能很好地工作,并成功地用于某些药物制剂中的洛哌丁胺分析。

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