• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>International Journal of Electrochemical Science >Electrochemical Oxidation and Amperometric Determination of Isoniazid at Functionalized Multiwalled Carbon Nanotube Modified Electrode
【24h】

Electrochemical Oxidation and Amperometric Determination of Isoniazid at Functionalized Multiwalled Carbon Nanotube Modified Electrode

机译：功能化多壁碳纳米管修饰电极对异烟肼的电化学氧化和安培测定

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

In this work we report the fabrication of an electrochemical sensor for the amperometric determinationof isoniazid (ISN) based on functionalized multiwalled carbon nanotube (f-MWCNT) modified glassycarbon electrode (GCE). f-MWCNT has been synthesized by acid treatment of MWCNT byultrasonication. The voltammetric behavior of ISN at various carbon nanomaterials such as MWCNT,f-MWCNT, graphene oxide, reduced-graphene oxide, bare GCE, etc have been studied by cyclicvoltammetry (CV). ISN undergoes electrochemical oxidation at all the aforementioned nanomaterialsmodified electrodes. However, f-MWCNT film modified GCE shows the maximum peak current forISN among the various carbon nanomaterials, which is 7.11 times higher than that obtained atMWCNT film. ISN undergoes an irreversible oxidation at f-MWCNT film in pH 4 at 0.4V which iswell defined and it can be utilized for electroanalytical purposes. ISN showed fast amperometricresponse at f-MWCNT modified GCE with a good linear range of detection 1 to 70 M ISN. The filmshowed good background current stability and excellent performance in pharmaceutical sampleanalysis with good reproducibility.
机译：在这项工作中，我们报告了基于功能化的多壁碳纳米管（f-MWCNT）修饰玻碳电极（GCE）的用于电流测定异烟肼（ISN）的电化学传感器的制造。 f-MWCNT是通过超声波处理对MWCNT进行酸处理而合成的。通过循环伏安法（CV）研究了ISN在各种碳纳米材料如MWCNT，f-MWCNT，氧化石墨烯，还原氧化石墨烯，裸露的GCE等上的伏安行为。 ISN在所有上述纳米材料修饰的电极上进行电化学氧化。但是，f-MWCNT膜修饰的GCE在各种碳纳米材料中显示出ISN的最大峰值电流，比在MWCNT膜上获得的峰值电流高7.11倍。 ISN在0.4伏的pH值为4的f-MWCNT膜上经历了不可逆的氧化，该氧化作用很明确，可用于电分析目的。 ISN在f-MWCNT修饰的GCE上显示出快速的安培响应，并具有1到70 M ISN的良好线性检测范围。该膜显示出良好的背景电流稳定性，并在药物样品分析中具有优异的性能，并具有良好的重现性。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号