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首页> 外文期刊>International Journal of Electrochemical Science >Ultra-Sensitive Aptasensor Based on IL and Fe3O4 Nanoparticles for Tetracycline Detection
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Ultra-Sensitive Aptasensor Based on IL and Fe3O4 Nanoparticles for Tetracycline Detection

机译：基于IL和Fe 3 O 4 纳米粒子的超灵敏适应传感器用于四环素的检测

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摘要

An aptasensor for detecting tetracycline residues in milk was fabricated by depositing an ionic liquid (IL) and Fe3O4 magnetic nanoparticles onto a screen-printed electrode (SPE). IL has great conductivity and a large electrochemical window, making it a new green medium for such devices. Fe3O4 enhances electrochemical signals and forms films on surfaces well. As the composite mediators, these materials not only accelerated electron transfer but also improved the response speed and precision of the aptasensor. Herein, the synergistic effect of IL and Fe3O4 was exploited to construct a sensing interface for amplifying signals. The proposed aptasensor was capable of detecting tetracycline as demonstrated here. The detection range of the aptasensor was 1.0 nM to 1.0×107 nM with a detection limit of 1.0 nM, which is much lower than the maximum residue limit allowed by international regulations (224 nM). The aptasensor demonstrated good selectivity, reproducibility, and stability. Additionally, the sensor can be configured for the detection of other antibiotics.
机译：通过将离子液体（IL）和Fe3O4磁性纳米粒子沉积到丝网印刷电极（SPE）上，制造了用于检测牛奶中四环素残留的适体传感器。 IL具有出色的电导率和较大的电化学窗口，使其成为此类设备的新绿色介质。 Fe 3 O 4增强电化学信号并在表面上很好地形成膜。作为复合介质，这些材料不仅加速了电子传递，而且还提高了适体传感器的响应速度和精度。在此，利用IL和Fe 3 O 4的协同作用来构建用于放大信号的感测接口。如此处所示，拟议的适体传感器能够检测四环素。适体传感器的检测范围为1.0 nM至1.0×107 nM，检测限为1.0 nM，远低于国际法规所允许的最大残留限度（224 nM）。适体传感器表现出良好的选择性，重现性和稳定性。另外，传感器可以配置用于检测其他抗生素。

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