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首页> 外文期刊>International Journal of Electrochemical Science >In Vitro Bioactivity, Degradation Property and Cell Viability of the CaP/Chitosan/Graphene Coating on Magnesium Alloy in m- SBF
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In Vitro Bioactivity, Degradation Property and Cell Viability of the CaP/Chitosan/Graphene Coating on Magnesium Alloy in m- SBF

机译：m-SBF中镁合金上CaP /壳聚糖/石墨烯涂层的体外生物活性，降解特性和细胞活力

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摘要

CaP/chitosan/graphene coating on Mg alloy was obtained by electrophoretic deposition (EPD) andtransformation in a phosphate buffer solution (PBS). The microstructures and compositions of thecomposite coatings were studied by scanning electron microscope (SEM), Fourierransformedinfrared spectroscopy (FTIR), X-ray diffraction (XRD) and Raman spectroscopy. The elementconcentration was investigated by inductively coupled plasma optical emission spectrometer (ICP- OES) test. The degradation behavior of Mg based CaP/chitosan/graphene in m-SBF was researched bysoaking experiment and electrochemical performance test. The cytotoxicity of the prepared material toSaOS-2 cells was determined by CCK assay. The results indicated that addition of graphene had apositive effect on improving the bioactivity and cell viability of the CaP/chitosan coating.CaP/chitosan/graphene coating could protect the Mg alloy from corroding in m-SBF.
机译：通过电泳沉积（EPD）和在磷酸盐缓冲溶液（PBS）中转化获得了在Mg合金上的CaP /壳聚糖/石墨烯涂层。通过扫描电子显微镜（SEM），傅立叶红外光谱（FTIR），X射线衍射（XRD）和拉曼光谱研究了复合涂层的微观结构和组成。通过电感耦合等离子体发射光谱仪（ICP-OES）测试来研究元素浓度。通过浸泡实验和电化学性能试验研究了Mg基CaP /壳聚糖/石墨烯在m-SBF中的降解行为。通过CCK测定法确定所制备的材料对SaOS-2细胞的细胞毒性。结果表明，石墨烯的添加对提高CaP /壳聚糖涂层的生物活性和细胞活力具有积极的作用.CaP /壳聚糖/石墨烯涂层可以防止Mg合金在m-SBF中腐蚀。

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