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首页> 外文期刊>International Journal of Electrochemical Science >Fabrication of Multifunctional Biosensor for the Determination of Hydrogen Peroxide, Dopamine and Uric Acid
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Fabrication of Multifunctional Biosensor for the Determination of Hydrogen Peroxide, Dopamine and Uric Acid

机译：用于测定过氧化氢，多巴胺和尿酸的多功能生物传感器的制造

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摘要

A novel multifunctional biosensor was prepared by dropping graphene on the 2-Amino-thiazol (AT)film at glassy carbon electrode (GCE). The surface morphology of graphene, AT and graphene-ATfilm modified GCE has been examined by using SEM and AFM. The advantages of proposed filmwere demonstrated for the determination of H2O2 reduction using amperometric, DA and UA oxidationusing differential pulse voltammetry. The graphene-AT/GCE as a multifunctional biosensor exhibited-5 -4 -6 a linear response range for H2O2 determine (from 1.00 to 3.10 M), low detection limit (10-1 -2 M), high sensitivity (1.73 mA mM cm ) and the relative standard deviation (RSD %) less than 2% (n= 5). Similarly, the multifunctional biosensor can simultaneously determine the DA and UA with the-6 -5 interference of AA. For the linear response range of DA and UA were from 50 to 2.50 M and-6 -4 2.50 to 1.250 M. In addition, the multifunctional biosensor by graphene-AT film modifiedGCE was advantageous in terms of its simple preparation, specificity, stability and selectivity.
机译：通过将石墨烯滴在玻璃碳电极（GCE）的2-氨基噻唑（AT）膜上，制备了一种新型的多功能生物传感器。利用SEM和AFM对石墨烯，AT和石墨烯-AT膜修饰的GCE的表面形貌进行了研究。在使用安培法，DA和UA氧化和差分脉冲伏安法测定H2O2还原量时，已证明了所建议膜的优势。作为多功能生物传感器的石墨烯-AT / GCE表现出-5 -4 -6对H2O2测定的线性响应范围（从1.00至3.10 M），低检测限（10-1 -2 M），高灵敏度（1.73 mA mM） ，相对标准偏差（RSD％）小于2％（n = 5）。类似地，多功能生物传感器可以同时通过AA的-6 --5干扰确定DA和UA。 DA和UA的线性响应范围分别为50至2.50 M和-6 -4 2.50至1.250M。此外，石墨烯-AT膜修饰的GCE多功能生物传感器在制备简单，特异性，稳定性和稳定性方面均具有优势。选择性。

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