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Parental Supply of Alcohol in Childhood and Risky Drinking in Adolescence: Systematic Review and Meta-Analysis

机译:父母在儿童期的酒精供应和青春期的危险饮酒:系统评价和荟萃分析

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Whether parental supply of alcohol affects the likelihood of later adolescent risky drinking remains unclear. We conducted a systematic review and meta-analysis to synthesize findings from longitudinal studies investigating this association. We searched eight electronic databases up to 10 September 2016 for relevant terms and included only original English language peer-reviewed journal articles with a prospective design. Two reviewers independently screened articles, extracted data and assessed risk of bias. Seven articles met inclusion criteria, six of which used analytic methods allowing for meta-analysis. In all seven studies, the follow-up period was ≥12 months and attrition ranged from 3% to 15%. Parental supply of alcohol was associated with subsequent risky drinking (odds ratio = 2.00, 95% confidence interval = 1.72, 2.32); however, there was substantial risk of confounding bias and publication bias. In all studies, measurement of exposure was problematic given the lack of distinction between parental supply of sips of alcohol versus whole drinks. In conclusion, parental supply of alcohol in childhood is associated with an increased likelihood of risky drinking later in adolescence. However, methodological limitations preclude a causal inference. More robust longitudinal studies are needed, with particular attention to distinguishing sips from whole drinks, measurement of likely confounders, and multivariable adjustment.
机译:父母的酒精供应是否会影响后期青少年饮酒的可能性尚不清楚。我们进行了系统的综述和荟萃分析,以综合研究这种关联的纵向研究的发现。截至2016年9月10日,我们在八个电子数据库中搜索了相关术语,并且仅包含具有前瞻性设计的原始英语同行评审期刊文章。两名审稿人独立筛选文章,提取数据并评估偏见风险。七篇文章符合纳入标准,其中六篇使用分析方法进行荟萃分析。在所有七项研究中,随访期均≥12个月,损耗率为3%至15%。父母的酒精供应与随后的危险饮酒有关(赔率= 2.00,95%的置信区间= 1.72,2.32);但是,存在将偏差和出版偏差混淆的巨大风险。在所有研究中,由于父母饮酒量与全脂饮料之间没有区别,暴露量的测量存在问题。总之,儿童期父母的酒精供应与青春期后期高风险饮酒的可能性增加有关。但是,方法的局限性排除了因果推论。需要进行更强大的纵向研究,尤其要注意从全脂饮料中区分饮酒,可能的混杂因素的测量以及多变量调整。

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