...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>International Journal of Environmental Research and Public Health >A Meta-Regression Analysis of the Effectiveness of Mosquito Nets for Malaria Control: The Value of Long-Lasting Insecticide Nets
【24h】

A Meta-Regression Analysis of the Effectiveness of Mosquito Nets for Malaria Control: The Value of Long-Lasting Insecticide Nets

机译：蚊帐对疟疾控制效果的Meta回归分析：持久性杀虫剂网的价值

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Long-lasting insecticidal nets (LLINs) have been widely used as an effective alternative to conventional insecticide-treated nets (ITNs) for over a decade. Due to the growing number of field trials and interventions reporting the effectiveness of LLINs in controlling malaria, there is a need to systematically review the literature on LLINs and ITNs to examine the relative effectiveness and characteristics of both insecticide nettings. A systematic review of over 2000 scholarly articles published since the year 2000 was conducted. The odds ratios (ORs) of insecticidal net effectiveness in reducing malaria were recorded. The final dataset included 26 articles for meta-regression analysis, with a sample size of 154 subgroup observations. While there is substantial heterogeneity in study characteristics and effect size, we found that the overall OR for reducing malaria by LLIN use was 0.44 (95% CI = 0.41–0.48, p 0.01) indicating a risk reduction of 56%, while ITNs were slightly less effective with an OR of 0.59 (95% CI = 0.57–0.61, p 0.01). A meta-regression model confirms that LLINs are significantly more effective than ITNs in the prevention of malaria, when controlling for other covariates. For both types of nets, protective efficacy was greater in high transmission areas when nets were used for an extended period. However, cross-sectional studies may overestimate the effect of the nets. The results surprisingly suggest that nets are less effective in protecting children under the age of five, which may be due to differences in child behavior or inadequate coverage. Compared to a previous meta-analysis, insecticide-treated nets appear to have improved their efficacy despite the risks of insecticide resistance. These findings have practical implications for policymakers seeking effective malaria control strategies.
机译：十多年来，长效杀虫网（LLIN）被广泛用作传统杀虫剂处理过的网（ITN）的有效替代品。由于越来越多的实地试验和干预措施报告了LLIN在控制疟疾方面的有效性，因此有必要系统地审查LLIN和ITN的文献，以研究两种杀虫剂网的相对有效性和特征。对2000年以来发表的2000余篇学术文章进行了系统回顾。记录了减少疟疾的杀虫净效力的比值比（OR）。最终的数据集包括用于元回归分析的26篇文章，样本大小为154个亚组观察值。尽管研究特征和效应大小存在很大的异质性，但我们发现通过使用LLIN减少疟疾的总体OR为0.44（95％CI = 0.41-0.48，p <0.01），表明降低了56％的风险，而ITNs为OR为0.59时效果稍差（95％CI = 0.57–0.61，p <0.01）。荟萃回归模型证实，在控制其他协变量时，LLIN在预防疟疾方面比ITN有效得多。对于这两种类型的蚊帐，如果长时间使用蚊帐，在高透光率区域的防护效果会更高。但是，横断面研究可能会高估网的效果。结果出乎意料地表明，蚊帐在保护五岁以下儿童方面效果较差，这可能是由于儿童行为差异或覆盖范围不足所致。与以前的荟萃分析相比，尽管有抗药性的风险，但经过杀虫剂处理的网似乎已经提高了其功效。这些发现对寻求有效疟疾控制策略的决策者具有实际意义。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号