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首页> 外文期刊>International Journal of Environmental Research and Public Health >A Gastroenteritis Outbreak Caused by Noroviruses in Greece
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A Gastroenteritis Outbreak Caused by Noroviruses in Greece

机译：希腊诺如病毒引起的肠胃炎暴发

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In June 2006, an outbreak alert regarding cases of acute gastroenteritis in a region in North Eastern Greece (population 100,882 inhabitants), triggered investigations to guide control measures. The outbreak started the first days of June, and peaked in July. A descriptive epidemiological study, a virological characterization of the viral agent identified from cases as well as a phylogenetic analysis was performed. From June 5 to September 3, 2006 (weeks 23–44), 1,640 cases of gastroenteritis (45.2% male and 54.8% female, aged 3 months to 89 years) were reported. The overall attack rate for the period was 16.3 cases/1,000 inhabitants. About 57% of cases observed were under the age of 15 years. Αnalysis of faecal samples identified Norovirus GII strains. Fifteen different Norovirus GII strains were recorded, presenting a homology of 94.8% (86–97%) to GII strains obtained from GenBank. The long duration of the outbreak suggests an important role of person-to-person transmission, while the emergence of the outbreak was possibly due to contaminated potable water, although no viruses were detected in any tested water samples. This outbreak underscores the need for a national surveillance system for acute non-bacterial gastroenteritis outbreaks.
机译：2006年6月，关于希腊东北部一个地区（人口100882居民）的急性胃肠炎病例的暴发警报触发了调查，以指导控制措施。爆发始于6月的第一天，并于7月达到顶峰。进行了描述性流行病学研究，从病例中鉴定出的病毒制剂的病毒学特征以及系统发育分析。从2006年6月5日至9月3日（第23-44周），报告了1,640例胃肠炎（男45.2％，女54.8％，年龄3个月至89岁）。在此期间，总发作率是16.3例/ 1,000居民。观察到的病例中约57％在15岁以下。粪便样品的分析鉴定出诺如病毒GII株。记录了15种不同的诺如病毒GII菌株，与从GenBank获得的GII菌株具有94.8％（86-97％）的同源性。暴发的持续时间长，表明了人与人之间传播的重要作用，而暴发的发生可能是由于饮用水被污染，尽管在任何测试的水样中均未检测到病毒。这次暴发突显了对急性非细菌性胃肠炎暴发的国家监测系统的需求。

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