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首页> 外文期刊>International Journal of Environmental Research and Public Health >Different Risk Factors for Very Low Birth Weight, Term-Small-for-Gestational-Age, or Preterm Birth in Japan
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Different Risk Factors for Very Low Birth Weight, Term-Small-for-Gestational-Age, or Preterm Birth in Japan

机译：日本极低的出生体重，足月的小胎龄或早产的不同风险因素

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From 1985 to 2013, the mean birth weight of infants in Japan decreased from 3120 g to 3000 g, and the low-birth-weight rate among live births increased from 6.3% to 9.6%. No prospective study has elucidated the risk factors for poor fetal growth and preterm birth in recent Japanese parents, such as increased parental age, maternal body figure, assisted reproductive technology (ART), and socioeconomic status. Participants were mother–infant pairs ( n = 18,059) enrolled in a prospective birth cohort in Hokkaido, Japan from 2002 to 2013. Parental characteristics were obtained via self-reported questionnaires during pregnancy. Medical records helped identify very-low-birth-weight (VLBW; 1500g), term-small-for-gestational-age (term-SGA), and preterm-birth (PTB; 37 weeks) infants. We calculated relative risks (RRs) for PTB, VLBW, and term-SGA birth based on parental characteristics. The prevalence of PTB, VLBW, and term-SGA was 4.5%, 0.4%, and 6.5%, respectively. Aged parents and ART were risk factors for PTB and VLBW. Maternal alcohol drinking during pregnancy increased the risk; a parental educational level of ≥16 years reduced risk of term-SGA. Maternal pre-pregnancy BMI of 18.5 kg/m 2 increased the risk of PTB and term-SGA. The RR for low BMI was highest among mothers who have low educational level. Among various factors, appropriate nutritional education to maintain normal BMI is important to prevent PTB and term-SGA in Japan.
机译：从1985年到2013年，日本婴儿的平均出生体重从3120克降低到3000克，活产婴儿的低出生体重比率从6.3％增加到9.6％。尚无前瞻性研究阐明近期日本父母胎儿生长不良和早产的危险因素，例如父母年龄增加，孕产妇身材，辅助生殖技术（ART）和社会经济状况。参加者为2002年至2013年在日本北海道参加前瞻性出生队列的母婴对（n = 18,059）。父母的特征通过怀孕期间通过自我报告的问卷获得。病历有助于确定极低出生体重（VLBW; <1500g），足月小胎龄婴儿（term-SGA）和早产婴儿（PTB; <37周）。我们根据父母的特征计算了PTB，VLBW和足月SGA出生的相对风险（RRs）。 PTB，VLBW和SGA期限的患病率分别为4.5％，0.4％和6.5％。年迈的父母和ART是PTB和VLBW的危险因素。孕期孕妇饮酒会增加患病风险; ≥16岁的父母教育水平可降低足月SGA的风险。孕前BMI <18.5 kg / m 2的孕妇增加了PTB和足月SGA的风险。受教育程度低的母亲中，低BMI的RR最高。在各种因素中，适当的营养教育以维持正常的BMI对预防日本的PTB和足月SGA很重要。

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