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首页> 外文期刊>International Journal of Environmental Research and Public Health >Real World Study to Evaluate the Effectiveness of Varenicline and Cognitive-Behavioural Interventions for Smoking Cessation
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Real World Study to Evaluate the Effectiveness of Varenicline and Cognitive-Behavioural Interventions for Smoking Cessation

机译：评估伏伦替林和认知行为干预对戒烟有效性的真实世界研究

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A prospective pragmatic interventional study was conducted to evaluate the effectiveness of varenicline for smoking cessation among a cohort of motivated smokers attending two smoking cessation clinics. Smokers between 18 and 65 years who had smoked 10 or more cigarettes per day were included. All participants received cognitive-behavioural varenicline according to approved dose and prescriptions. Continuous abstinence, validated by exhaled CO levels, was assessed in each control. A total of 264 smokers – 155 males (58.7%) and 109 females (41.3%) – were included. Mean age was 43.7, amount smoked was 23 cigarettes per day and 61.4% had at least one prior attempt to quit. The continuous abstinence rate at end of treatment (12 wks) was 58.3%. Conclusions: varenicline and cognitive-behavioural intervention are effective for smoking cessation with high continuous abstinence rates when are used in a clinical setting.
机译：进行了一项前瞻性的实用干预性研究，以评估在两个有戒烟门诊的积极吸烟者中，缬尼克兰对戒烟的有效性。包括每天吸烟10支或以上的18至65岁之间的吸烟者。根据批准的剂量和处方，所有参与者都接受了认知行为伐尼克兰。在每个对照中评估了持续的禁欲，并通过呼出的CO水平进行了验证。总共包括264名吸烟者-男性155名（58.7％）和女性109名（41.3％）。平均年龄为43.7岁，每天吸烟量为23支香烟，并且61.4％的人至少有一次尝试戒烟。治疗结束时（12 wks）的持续戒断率为58.3％。结论：当用于临床环境时，缬尼克林和认知行为干预对戒烟有效，持续戒断率高。

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