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首页> 外文期刊>International Journal of Environmental Research and Public Health >The Association of Hypertriglyceridemic Waist Phenotype with Chronic Kidney Disease and Its Sex Difference: A Cross-Sectional Study in an Urban Chinese Elderly Population
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The Association of Hypertriglyceridemic Waist Phenotype with Chronic Kidney Disease and Its Sex Difference: A Cross-Sectional Study in an Urban Chinese Elderly Population

机译：高甘油三酸酯腰围表型与慢性肾脏病的关联及其性别差异：在中国城市老年人口中的横断面研究

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Background : The primary objective of this study was to explore the association of hypertriglyceridemic waist (HTGW) phenotype with chronic kidney disease (CKD) and its sex difference in an urban Chinese elderly population. Methods : In a cross-sectional study, a total of 2102 participants aged 60–95 years were recruited and classified into four phenotypes: normal waist-normal triglyceride (NWNT), normal waist-elevated triglycerides (NWET), elevated waist-normal triglycerides (EWNT), and HTGW. Logistic regression analysis was used to estimate the associations of interest. Results : Total prevalence of CKD was 12.6%, and the CKD prevalence in participants with EWNT and HTGW was higher than with NWNT and NWET without regard to sex. Compared to NWNT phenotype, the adjusted OR for CKD was 1.95 (95% CI: 1.32–2.88) in HTGW groups. In contrast with the null findings (OR: 1.66; 95% CI: 0.94–2.94) in women after additional adjustment for diabetes and hypertension, the OR with HTGW remained strong (OR: 1.88; 95% CI: 1.04–3.39) in men. Similar findings appeared with the EWNT phenotype. Conclusions : The HTGW phenotype is positively associated with CKD among Chinese community elderly and may have a greater impact on men. More attention should be paid to the association between triglycerides and waist circumference in clinical practice and to the further identification this uncertain sex-related association.
机译：背景：本研究的主要目的是探讨中国城市老年人口中高甘油三酯腰（HTGW）表型与慢性肾脏病（CKD）的关系及其性别差异。方法：在一项横断面研究中，共招募了2102名年龄在60-95岁之间的参与者，并将其分为四种表型：正常腰围正常甘油三酸酯（NWNT），正常腰围升高甘油三酸酯（NWET），腰围正常甘油三酸酯升高（EWNT）和HTGW。使用逻辑回归分析来估计感兴趣的关联。结果：CKNT的总患病率为12.6％，而不论性别，EWNT和HTGW参与者的CKD患病率均高于NWNT和NWET参与者。与NWNT表型相比，HTGW组的CKD校正OR为1.95（95％CI：1.32–2.88）。与对糖尿病和高血压进行进一步调整的女性无效结果（OR：1.66; 95％CI：0.94-2.94）相比，HTGW的OR仍然很强（OR：1.88; 95％CI：1.04-3.39）。 。 EWNT表型也出现了类似的发现。结论：HTGW表型与中国社区老年人的CKD呈正相关，可能对男性影响更大。在临床实践中应更加注意甘油三酸酯与腰围之间的关联，并应进一步识别这种不确定的性别关联。

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