The present report shows that nicotine enhances some of alcohol’s positive and negative effects in women and that these effects are most pronounced during the luteal phase of the menstrual cycle. Ten low progesterone and 10 high progesterone/luteal-phase women received nicotine patch pretreatments (placebo or 21 mg) 3 hours before an alcohol challenge (0.4 g/kg). Subjective effects were recorded on mood adjective scales and the Addiction Research Center Inventory (ARCI). Heart rate and skin temperature were recorded. Luteal-phase women reported peak positive (e.g. “stimulated”) and peak negative effects (e.g. “clumsy”, “dizzy”) almost twice as great as low progesterone women.
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机译：本报告显示，尼古丁可增强女性酒精的某些正面和负面影响，而这些影响在月经的黄体期最为明显。 10名低孕酮和10名高孕酮/黄体期妇女在酒精攻击（0.4 g / kg）前3小时接受了尼古丁贴片预处理（安慰剂或21 mg）。在情绪形容词量表和成瘾研究中心量表（ARCI）上记录主观效果。记录心率和皮肤温度。黄体期妇女的阳性反应峰值（例如“刺激”）和阴性反应峰值（例如“笨拙”，“头晕”）几乎是孕激素含量低的妇女的两倍。
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