• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>International Journal of Environmental Research and Public Health >Exposure to Multiple Pesticides and Risk of Non-Hodgkin Lymphoma in Men from Six Canadian Provinces
【24h】

Exposure to Multiple Pesticides and Risk of Non-Hodgkin Lymphoma in Men from Six Canadian Provinces

机译：来自加拿大六个省的男性中多种农药的暴露和非霍奇金淋巴瘤的风险

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Non-Hodgkin lymphoma (NHL) has been linked to several agricultural exposures, including some commonly used pesticides. Although there is a significant body of literature examining the effects of exposure to individual pesticides on NHL, the impact of exposure to multiple pesticides or specific pesticide combinations has not been explored in depth. Data from a six-province Canadian case-control study conducted between 1991 and 1994 were analyzed to investigate the relationship between NHL, the total number of pesticides used and some common pesticide combinations. Cases (n = 513) were identified through hospital records and provincial cancer registries and controls (n = 1,506), frequency matched to cases by age and province of residence, were obtained through provincial health records, telephone listings, or voter lists. In multiple logistic regression analyses, risk of NHL increased with the number of pesticides used. Similar results were obtained in analyses restricted to herbicides, insecticides and several pesticide classes. Odds ratios increased further when only ‘potentially carcinogenic’ pesticides were considered (OR[one pesticide] = 1.30, 95% CI = 0.90–1.88; OR[two to four] = 1.54, CI = 1.11–2.12; OR[five or more] = 1.94, CI = 1.17–3.23). Elevated risks were also found among those reporting use of malathion in combination with several other pesticides. These analyses support and extend previous findings that the risk of NHL increases with the number of pesticides used and some pesticide combinations.
机译：非霍奇金淋巴瘤（NHL）与多种农业暴露有关，包括一些常用农药。尽管有大量文献研究了接触各种农药对NHL的影响，但尚未深入探讨接触多种农药或特定农药组合的影响。分析了从1991年至1994年在加拿大进行的六个省的病例对照研究中的数据，以调查NHL，所用农药总数和某些常见农药组合之间的关系。通过医院记录和省癌症登记和控制（n = 1,506）确定病例（n = 513），其频率与年龄和居住省份相匹配，是通过省健康记录，电话清单或选民名单获得的。在多项逻辑回归分析中，NHL的风险随着所使用农药的数量而增加。在仅限于除草剂，杀虫剂和几种农药类别的分析中获得了相似的结果。当仅考虑“潜在致癌”农药时，几率进一步增加（OR [一种农药] = 1.30，95％CI = 0.90–1.88; OR [2至4] = 1.54，CI = 1.11–2.12; OR [5以上] = 1.94，CI = 1.17–3.23）。在报告与其他几种农药合用马拉硫磷的人中，也发现了较高的风险。这些分析支持并扩展了先前的发现，即随着使用的农药数量和某些农药组合的增加，NHL的风险会增加。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号