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首页> 外文期刊>International Journal of Environmental Research and Public Health >Associations of Serum 25-Hydroxyvitamin D with Physical Performance and Bone Health in Overweight and Obese Older Adults
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Associations of Serum 25-Hydroxyvitamin D with Physical Performance and Bone Health in Overweight and Obese Older Adults

机译：血清25-羟维生素D与超重和肥胖老年人的身体表现和骨骼健康的关系

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摘要

Low vitamin D status commonly accompanies obesity, and both vitamin D deficiency and obesity have been associated with falls and fracture risk in older adults. We aimed to determine the associations of serum 25-hydroxyvitamin D (25(OH)D) concentrations with physical performance and bone health in community-dwelling, overweight and obese older men and women. Serum 25(OH)D concentrations were measured in 84 participants with body mass index ≥25 kg/m 2 (mean ± SD age 62.4 ± 7.9 years; 55% women). Physical function was determined by short physical performance battery, hand grip and quadriceps strength, and stair climb power tests. Body composition and bone structure were assessed by dual-energy X-ray absorptiometry and peripheral quantitative computed tomography, respectively. Mean ± SD 25(OH)D was 49.6 ± 17.7 nmol/L, and 50% of participants had low 25(OH)D (50 nmol/L) levels. 25(OH)D concentrations were positively associated with quadricep strength and stair climb power in women (B = 0.15; 95% CI 0.02–0.27 kg and B = 1.07; 95% CI 0.12–2.03 W, respectively) but not in men. There were no associations between 25(OH)D and bone parameters in either sex after multivariable adjustment (all p 0.05). Lower 25(OH)D concentrations are associated with poorer quadricep strength and muscle power in overweight and obese older women but not men.
机译：肥胖通常伴随着低维生素D状态，并且维生素D缺乏和肥胖都与老年人跌倒和骨折风险有关。我们旨在确定社区居民，超重和肥胖的老年男女中血清25-羟基维生素D（25（OH）D）浓度与身体表现和骨骼健康的关系。在84名体重指数≥25kg / m 2的参与者中测量血清25（OH）D浓度（平均±SD年龄为62.4±7.9岁; 55％为女性）。身体机能由短时的体能表现，手握力和股四头肌力量以及楼梯爬升功率测试确定。身体成分和骨骼结构分别通过双能X射线吸收法和外周定量计算机断层扫描进行评估。平均±SD 25（OH）D为49.6±17.7 nmol / L，50％的参与者的25（OH）D低（<50 nmol / L）。女性的25（OH）D浓度与四头肌力量和爬楼梯能力呈正相关（分别为B = 0.15; 95％CI 0.02–0.27 kg和B = 1.07; 95％CI 0.12–2.03 W），而男性则没有。多变量调整后，男女性别的25（OH）D与骨参数之间均无关联（所有p> 0.05）。在超重和肥胖的老年妇女中，较低的25（OH）D浓度与较差的股四头肌力量和肌肉力量有关，而与男性无关。

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