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A Systematic Review and Meta-Analysis of Dengue Risk with Temperature Change

机译:温度变化对登革热风险的系统评价和荟萃分析

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Dengue fever (DF) is the most serious mosquito-borne viral disease in the world and is significantly affected by temperature. Although associations between DF and temperatures have been reported repeatedly, conclusions have been inconsistent. Six databases were searched up to 23 March 2014, without language and geographical restrictions. The articles that studied the correlations between temperatures and dengue were selected, and a random-effects model was used to calculate the pooled odds ratio and 95% confidence intervals. Of 1589 identified articles, 137 were reviewed further, with 33 satisfying inclusion criteria. The closest associations were observed between mean temperature from the included studies (23.2–27.7 °C) and DF (OR 35.0% per 1 °C; 95% CI 18.3%–51.6%) positively. Additionally, minimum (18.1–24.2 °C) (29.5% per 1 °C; 20.9%–38.1%) and maximum temperature (28.0–34.5 °C) (28.9%; 10.3%–47.5%) were also associated with increased dengue transmission. The OR of DF incidence increased steeply from 22 °C to 29 °C, suggesting an inflexion of DF risk between these lower and upper limits of DF risk. This discovery is helpful for government decision-makers focused on preventing and controlling dengue in areas with temperatures within this range.
机译:登革热(DF)是世界上最严重的蚊媒病毒性疾病,受温度影响很大。尽管DF和温度之间的关联已被反复报道,但结论并不一致。截至2014年3月23日,已搜索了六个数据库,没有语言和地理限制。选择研究温度和登革热之间相关性的文章,并使用随机效应模型计算汇总比值比和95%置信区间。在1589篇确定的文章中,有137篇被进一步审查,其中33篇符合纳入标准。所纳入研究的平均温度(23.2–27.7°C)与DF(OR 35.0%/ 1°C; 95%CI 18.3%–51.6%)之间呈正相关。此外,登革热升高也与最低(18.1–24.2°C)(29.5%/ 1°C; 20.9%–38.1%)和最高温度(28.0–34.5°C)(28.9%; 10.3%–47.5%)相关。传播。 DF发生率的OR从22°C急剧上升至29°C,这表明DF风险的上下限介于DF风险的上限和下限之间。这一发现对致力于在此温度范围内预防和控制登革热的政府决策者很有帮助。

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