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首页> 外文期刊>International Journal of Environmental Research and Public Health >Factors Associated with Bone Health in Malaysian Middle-Aged and Elderly Women Assessed via Quantitative Ultrasound
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Factors Associated with Bone Health in Malaysian Middle-Aged and Elderly Women Assessed via Quantitative Ultrasound

机译：通过定量超声评估的马来西亚中年和老年妇女的骨骼健康相关因素

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摘要

Risk factors for osteoporosis may vary according to different populations. We aimed to investigate the relationship between risk factors of osteoporosis and bone health indices determined via calcaneal quantitative ultrasound (QUS) in a group of Malaysian women aged 50 years or above. A cross-sectional study was performed on 344 Malaysian women recruited from a tertiary medical centre in Kuala Lumpur, Malaysia. They answered a self-administered questionnaire on their social-demographic details, medical history, lifestyle, and physical activity status. Their height was measured using a stadiometer, and their body composition estimated using a bioelectrical impedance device. Their bone health status was determined using a water-based calcaneal QUS device that generated three indices, namely speed of sound (SOS), broadband ultrasound attenuation (BUA), and stiffness index (SI). A T-score was computed from SI values using a reference database from a mainland Chinese population. Women with three or more lifetime pregnancies, who were underweight and not drinking coffee had a significantly lower BUA. Stepwise multiple linear regression showed that SOS was predicted by age alone, BUA and SI by years since menopause, body mass index (BMI), and number of lifetime pregnancies, and T-score by years since menopause and percentage of body fat. As a conclusion, suboptimal bone health in middle-aged and elderly Malaysian women as indicated by QUS is associated with old age, being underweight, having a high body fat percentage, and a high number of lifetime pregnancies. Women having several risk factors should be monitored more closely to protect their bones against accelerated bone loss.
机译：骨质疏松的危险因素可能因不同人群而异。我们旨在调查一组年龄在50岁或以上的马来西亚女性的骨质疏松症危险因素与通过跟骨定量超声（QUS）测定的骨骼健康指标之间的关系。这项横断面研究对从马来西亚吉隆坡的一家三级医疗中心招募的344名马来西亚妇女进行了研究。他们回答了一份自我管理的问卷，内容涉及他们的社会人口统计学详细信息，病史，生活方式和体育锻炼状况。使用测距仪测量其身高，并使用生物电阻抗装置估算其身体成分。他们的骨骼健康状况是使用水基跟骨QUS设备确定的，该设备生成三个指标，即声速（SOS），宽带超声衰减（BUA）和刚度指标（SI）。使用来自中国大陆人口的参考数据库，根据SI值计算T分数。体重不足且不喝咖啡且一生中怀孕三个或三个以上的女性的BUA显着降低。逐步多元线性回归显示，SOS可以通过单独年龄，绝经后的年限，体重指数（BMI）和一生的怀孕次数来预测BUA和SI，而T值可以从绝经后的年限和体内脂肪百分比进行预测。结论是，如QUS所示，马来西亚中老年妇女的骨骼健康欠佳与老年，体重不足，体脂百分比高以及一生中大量怀孕有关。具有多个危险因素的女性应受到更密切的监视，以保护其骨骼免于加速骨质流失。

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