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首页> 外文期刊>International Journal of Environmental Research and Public Health >Increased Long-Term Mortality among Black CABG Patients Receiving Preoperative Inotropic Agents
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Increased Long-Term Mortality among Black CABG Patients Receiving Preoperative Inotropic Agents

机译:接受术前正性肌力药物的黑人CABG患者的长期死亡率增加

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The aim of this study was to examine racial differences in long-term mortality after coronary artery bypass grafting (CABG), stratified by preoperative use of inotropic agents. Black and white patients who required preoperative inotropic support prior to undergoing CABG procedures between 1992 and 2011 were compared. Mortality probabilities were computed using the Kaplan-Meier product-limit method. Hazard ratios (HR) and 95% confidence intervals (CI) were computed using a Cox regression model. A total of 15,765 patients underwent CABG, of whom 211 received preoperative inotropic agents within 48 hours of surgery. Long-term mortality differed by race (black versus white) among preoperative inotropic category (inotropes: adjusted HR = 1.6, 95% CI = 1.009–2.4; no inotropes: adjusted HR = 1.15, 95% CI = 1.08–1.2; Pinteraction < 0.0001). Our study identified an independent preoperative risk-factor for long-term mortality among blacks receiving CABG. This outcome provides information that may be useful for surgeons, primary care providers, and their patients.
机译:这项研究的目的是检查术前使用正性肌力药物分层对冠状动脉搭桥术(CABG)后长期死亡率的种族差异。比较了在1992年至2011年之间接受CABG手术之前需要术前正性肌力支持的黑人和白人患者。死亡率概率用Kaplan-Meier乘积极限法计算。使用Cox回归模型计算危险比(HR)和95%置信区间(CI)。总共15765名患者接受了CABG,其中211名在手术后48小时内接受了术前正性肌力药。术前正性肌力类别之间的长期死亡率因种族而异(黑与白)(正性肌力:调整后的HR = 1.6,95%CI = 1.009–2.4;无正性肌力:调整后的HR = 1.15,95%CI = 1.08– 1.2;交互作用<0.0001)。我们的研究确定了接受CABG的黑人中长期死亡率的独立的术前危险因素。该结果提供了可能对外科医生,初级保健提供者及其患者有用的信息。

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