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首页> 外文期刊>International Journal of General Medicine >Autologous cord blood harvesting in North Eastern Italy: ethical questions and emerging hopes for curing diabetes and celiac disease
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Autologous cord blood harvesting in North Eastern Italy: ethical questions and emerging hopes for curing diabetes and celiac disease

机译：意大利东北部自体脐血采集：治疗糖尿病和腹腔疾病的伦理学问题和新兴希望

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Background: The Friuli Venezia Giulia (FVG), a region of North Eastern Italy, has passed legislation (Decree No 2324/2010) to regulate the banking of umbilical cord blood samples for personal, autologous, or family-directed use, and to implement the Agreement of the State-Regions Permanent Conference (Decree No 62/CSR/2010). This paper aims to identify the formalities and the reasons why families collect and bank their cord blood in foreign banks for both personal and private use.Methods: To this end, at the Institute for Maternal and Child Health of Trieste (the regional capital city of the FVG), Italy, which assists about 1800 pregnant women a year, 129 questionnaires, drafted from January 2010 to December 2011 and concerning the granting of authorization to export samples, were examined.Results: The collected data showed that 75% of involved families had resorted to anonymous public collection, which is available to anyone with therapeutic needs, and provided compatibility and hematologic protocols recognized by the scientific and international community (main indications: leukemia, hemoglobinopaties, and inherited hematologic and immunologic disorders). Conversely, 25.0% requested private storage at a foreign bank for personal or family-dedicated use. The principal motivation by disease was for treatment for diabetes (22.4%) and celiac disease (19.7%) (a multiorgan disease for which the FVG region has provided safeguards by approving a specific law granting support to families; Decree No 561/2007). For these two types of disease we found that information was received from the internet and not from general medical physicians, with a significant difference found using the χ2 test (P < 0.01).Conclusion: The indication of treating these diseases with cord blood stem cell transplantation appears to be well grounded and encouraging, and has recently been corroborated by the international literature; however, the economic and social motivations promoting cord blood storage, for a fee, in the event of diseases that are still under study, require accurate information through general medical physicians on the actual possibilities of treatment.
机译：背景：意大利东北部地区的弗留利·威尼斯·朱利亚（FVG）已通过立法（第2324/2010号法令），以规范用于个人，自体或家庭定向使用的脐带血样品的保存，并实施州地区常设会议协定（第62 / CSR / 2010号法令）。本文旨在查明家庭为私人和私人目的而将脐带血收集并存入外国银行的手续和原因。方法：为此，在的里雅斯特的妇幼保健研究所（该地区的首都） （FVG），意大利，该组织每年协助约1800名孕妇，调查了从2010年1月至2011年12月起草的有关授权出口样品的129个问卷。结果：收集的数据显示，涉及家庭的75％曾采取匿名公开收藏，有治疗需要的任何人都可以使用，并提供了科学和国际社会认可的相容性和血液学方案（主要适应症：白血病，血红蛋白缺乏症以及遗传性血液学和免疫学疾病）。相反，有25.0％的人要求在外国银行存放私人存储以供个人或家庭专用。疾病的主要动机是治疗糖尿病（22.4％）和腹腔疾病（19.7％）（多器官疾病，FVG地区通过批准向家庭提供支持的具体法律来提供保障;第561/2007号法令）。对于这两种疾病，我们发现信息是从互联网上获得的，而不是从普通医学医生那里获得的，使用χ2检验发现存在显着差异（P <0.01）。结论：用脐带血干细胞治疗这些疾病的适应症移植似乎有充分的根据和令人鼓舞，最近国际文献证实了这一点。然而，在尚在研究中的疾病的情况下，收费的促进脐带血储存的经济和社会动机需要通过一般医学医生提供有关实际治疗可能性的准确信息。

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