...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>International Journal of Environmental Research and Public Health >Highly Pathogenic Avian Influenza H5N1 in Mainland China
【24h】

Highly Pathogenic Avian Influenza H5N1 in Mainland China

机译：中国大陆高度致病性禽流感H5N1

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Highly pathogenic avian influenza (HPAI) H5N1 has posed a significant threat to both humans and birds, and it has spanned large geographic areas and various ecological systems throughout Asia, Europe and Africa, but especially in mainland China. Great efforts in control and prevention of the disease, including universal vaccination campaigns in poultry and active serological and virological surveillance, have been undertaken in mainland China since the beginning of 2006. In this study, we aim to characterize the spatial and temporal patterns of HPAI H5N1, and identify influencing factors favoring the occurrence of HPAI H5N1 outbreaks in poultry in mainland China. Our study shows that HPAI H5N1 outbreaks took place sporadically after vaccination campaigns in poultry, and mostly occurred in the cold season. The positive tests in routine virological surveillance of HPAI H5N1 virus in chicken, duck, goose as well as environmental samples were mapped to display the potential risk distribution of the virus. Southern China had a higher positive rate than northern China, and positive samples were mostly detected from chickens in the north, while the majority were from duck in the south, and a negative correlation with monthly vaccination rates in domestic poultry was found (R = ?0.19, p value = 0.005). Multivariate panel logistic regression identified vaccination rate, interaction between distance to the nearest city and national highway, interaction between distance to the nearest lake and wetland, and density of human population, as well as the autoregressive term in space and time as independent risk factors in the occurrence of HPAI H5N1 outbreaks, based on which a predicted risk map of the disease was derived. Our findings could provide new understanding of the distribution and transmission of HPAI H5N1 in mainland China and could be used to inform targeted surveillance and control efforts in both human and poultry populations to reduce the risk of future infections.
机译：高致病性禽流感（HPAI）H5N1对人类和鸟类都构成了重大威胁，它已遍及亚洲，欧洲和非洲，尤其是在中国大陆，分布于广阔的地理区域和各种生态系统。自2006年初以来，中国已在控制和预防该疾病方面做出了巨大努力，包括在家禽中开展了全面疫苗接种运动以及进行了积极的血清学和病毒学监测。在本研究中，我们旨在表征HPAI的时空分布特征H5N1，并找出有利于中国大陆禽类HPAI H5N1爆发的因素。我们的研究表明，高致病性禽流感H5N1暴发是在禽类疫苗接种运动后零星发生的，并且多数发生在寒冷季节。对鸡，鸭，鹅和环境样品中HPAI H5N1病毒的常规病毒学监测中的阳性测试进行了绘图，以显示该病毒的潜在风险分布。华南地区的阳性率高于华北地区，北部地区的鸡大多检出阳性样本，而南部地区的鸭子则检出阳性样本，并且与家禽的月接种率呈负相关（R =？ 0.19，p值= 0.005）。多元面板Logistic回归确定疫苗接种率，距最近城市和国家公路的距离之间的相互作用，距最近湖泊和湿地的距离之间的相互作用，人口密度以及时空自回归项作为独立的危险因素HPAI H5N1爆发的发生，据此可以得出该疾病的预测风险图。我们的发现可以提供对HPAI H5N1在中国大陆分布和传播的新认识，并可用于指导人类和家禽种群的目标监测和控制工作，以减少未来感染的风险。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号