• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>International Journal of General Medicine >Pyogenic liver abscess and the emergence of Klebsiella as an etiology: a retrospective study
【24h】

Pyogenic liver abscess and the emergence of Klebsiella as an etiology: a retrospective study

机译：化脓性肝脓肿和克雷伯菌的病因学：一项回顾性研究

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Objectives: Pyogenic liver abscess (PLA) is a significant, though uncommon, cause of morbidity in the United States. Recently, Klebsiella has emerged as an important cause of PLA. We analyzed the clinical course, microbiology, and treatment outcomes of patients discharged with PLA. In addition, we sought to examine the incidence of and risk factors for Klebsiella liver abscess (KLA).Methods: We reviewed the charts of patients who discharged with PLA from two teaching hospitals in West Texas between January 1, 2007 and December 31, 2011.Results: We identified 49 cases of PLA. Abscess cultures were positive in 23 (48%) patients. The mean age of the cohort was 56 years (range: 20–83 years). Sixty percent were male. The most frequent conditions associated with PLA were intra-abdominal infections (ten cases; 20%), diabetes mellitus (nine cases; 18%) and malignancy (nine cases; 18%). Klebsiella was the most commonly isolated species from the abscess cultures (seven cases; 30% of all positive abscess cultures). We used univariate and logistic regression analyses to identify the risk factors for KLA. Controlling for age, only malignancy was identified in our cohort as a risk factor for a Klebsiella liver abscess. The overall mortality was 2%.Conclusion: Klebsiella is emerging as an important cause of liver abscesses. Malignancy may be an important risk factor for Klebsiella liver abscess.
机译：目的：化脓性肝脓肿（PLA）在美国是发病的重要原因，尽管不常见。最近，克雷伯菌已成为PLA的重要原因。我们分析了PLA出院患者的临床病程，微生物学和治疗结果。此外，我们还试图检查克雷伯氏菌肝脓肿（KLA）的发生率和危险因素。方法：我们回顾了2007年1月1日至2011年12月31日期间在西德克萨斯两所教学医院出院的PLA病人的图表结果：我们确定了49例PLA。 23例（48％）患者脓肿培养阳性。该队列的平均年龄为56岁（范围：20-83岁）。百分之六十是男性。与PLA相关的最常见疾病是腹腔内感染（十例; 20％），糖尿病（九例; 18％）和恶性肿瘤（九例; 18％）。克雷伯菌是脓肿培养物中最常见的分离物种（七例;占所有阳性脓肿培养物中的30％）。我们使用单变量和逻辑回归分析来确定KLA的危险因素。控制年龄，在我们的队列中仅将恶性肿瘤确定为克雷伯菌肝脓肿的危险因素。总死亡率为2％。结论：克雷伯菌已成为引起肝脓肿的重要原因。恶性肿瘤可能是克雷伯菌肝脓肿的重要危险因素。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号