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Coronary heart disease is not significantly linked to acute kidney injury identified using Acute Kidney Injury Group criteria

机译:冠心病与使用急性肾损伤组标准确定的急性肾损伤没有明显关系

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Background: Patients with unstable angina or myocardial infarction are at risk of acute kidney injury, which may be aggravated by the iodine-containing contrast agent used during coronary angiography; however, the relationship between these two conditions remains unclear.Objective: The current study investigated the relationship between acute kidney injury and coronary heart disease prior to coronary angiography.Methods: All patients were evaluated after undergoing coronary angiography in the cardiac catheterization laboratory of the Vinzentius Hospital in Landau, Germany, in 2011. The study group included patients with both acute coronary heart disease and acute kidney injury (as defined according to the classification of the Acute Kidney Injury Group); the control group included patients without acute coronary heart disease. Serum creatinine profiles were evaluated in all patients, as were a variety of demographic and health characteristics.Results: Of the 303 patients examined, 201 (66.34%) had coronary artery disease. Of these, 38 (18.91%) also had both acute kidney injury and acute coronary heart disease prior to and after coronary angiography, and of which in turn 34 (16.91%) had both acute kidney injury and acute coronary heart disease only prior to the coronary angiography. However, the occurrence of acute kidney injury was not significantly related to the presence of coronary heart disease (P = 0.95, Chi-square test).Conclusion: The results of this study indicate that acute kidney injury is not linked to acute coronary heart disease. However, physicians should be aware that many coronary heart patients may develop kidney injury while hospitalized for angiography.
机译:背景:患有不稳定型心绞痛或心肌梗塞的患者有发生急性肾脏损伤的危险,在冠状动脉造影期间使用含碘造影剂可能会加剧这种情况。目的:本研究调查了急性肾损伤与冠状动脉造影之前冠心病之间的关系。方法:所有患者均在Vinzentius心脏导管实验室接受冠状动脉造影后进行评估2011年,德国兰道的医院。研究组纳入了急性冠心病和急性肾损伤(根据急性肾损伤组的分类定义)的患者;对照组包括无急性冠心病的患者。对所有患者的血清肌酐谱进行了评估,并评估了各种人口统计学和健康特征。结果:在303例接受检查的患者中,有201例(66.34%)患有冠状动脉疾病。其中38例(18.91%)在冠状动脉造影之前和之后同时患有急性肾损伤和急性冠心病,其中34例(16.91%)仅在术前才同时患有急性肾损伤和急性冠心病。冠状动脉造影。但是,急性肾损伤的发生与冠心病的发生没有显着相关性(P = 0.95,卡方检验)。结论:本研究结果表明,急性肾损伤与急性冠心病没有关系。 。但是,医生应注意,许多冠心病患者在住院进行血管造影时可能会出现肾脏损伤。

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