• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>International Journal of General Medicine >Inflammatory status hepatic enzymes and serum creatinine in HIV-, HIV+ and HIV-TB co-infected adult Central Africans
【24h】

Inflammatory status hepatic enzymes and serum creatinine in HIV-, HIV+ and HIV-TB co-infected adult Central Africans

机译：HIV，HIV +和HIV-TB共同感染的成年中部非洲人的炎症状态肝酶和血清肌酐

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background and aim: Human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome is a major public health issue in Africa. The objective of this study was to determine which of isolated HIV-infection, isolated naive pulmonary tuberculosis (PTB), or naive HIV-PTB coinfection was more harmful to inflammatory, hepatic, and renal functions.Methods: This cross-sectional study was undertaken among ten patients with isolated HIV infection, ten patients with isolated naive HIV infection, ten patients with isolated PTB and 32 patients with HIV-PTB coinfection, with the aim of determining which group had the highest levels of oxidative stress and hepatic and renal dysfunction markers. Serum aminotransferase (AST), alanine transferase (ALT), gamma-glutamyl transferase (GGT), and creatinine measurements were compared across the three groups of patients, who were managed from admission in the pulmonology division of the Brazzaville Teaching Hospital, Congo.Results: HIV patients had the highest levels of ALT, GGT, and creatinine before and after adjusting for age and sex. Adjusted levels of AST, ALT, GGT, and creatinine were higher in HIV-PTB coinfection patients than in sero-negative PTB patients.Conclusion: There is a significant association between HIV infection and increase in concentration of ALT, GGT, and creatinine.
机译：背景与目的：人类免疫缺陷病毒（HIV）/后天免疫缺陷综合症是非洲的主要公共卫生问题。这项研究的目的是确定分离出的HIV感染，分离出的单纯性肺结核（PTB）或单纯性HIV-PTB合并感染对炎症，肝和肾功能的危害更大。在10例单纯性HIV感染患者，10例单纯性HIV感染患者，10例单纯性PTB患者和32例HIV-PTB合并感染患者中，目的是确定哪个组的氧化应激水平最高以及肝和肾功能障碍标记物。比较了三组患者的血清氨基转移酶（AST），丙氨酸转移酶（ALT），γ-谷氨酰转移酶（GGT）和肌酐的测量结果，这些患者是从刚果布拉柴维尔教学医院肺科住院治疗的。 ：调整年龄和性别前后，HIV患者的ALT，GGT和肌酐水平最高。 HIV-PTB合并感染患者中AST，ALT，GGT和肌酐的调整水平高于血清阴性PTB患者。结论：HIV感染与ALT，GGT和肌酐浓度升高之间存在显着相关性。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号