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首页> 外文期刊>International Journal of Environmental Research and Public Health >Air Manganese Levels and Chronic Liver Disease Mortality in North Carolina Counties: An Ecological Study
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Air Manganese Levels and Chronic Liver Disease Mortality in North Carolina Counties: An Ecological Study

机译：北卡罗莱纳州县的空气锰水平和慢性肝病死亡率：一项生态研究

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Manganese is an essential trace element which is toxic in high doses. Over the past several decades, manganese has replaced lead as the anti-knock agent in gasoline, raising concern about air and road-side contamination with this element. In addition, manganese is absorbed by the liver, making specific populations (e.g., pregnant women, infants and children, and patients with liver disease) susceptible to its toxic effects. Using data from the US Census Bureau, the North Carolina State Center for Health Statistics, and the US Environmental Protection Agency, this ecological study evaluated chronic liver disease mortality rates in North Carolina’s 100 counties. It correlated these rates with county-level demographics as well as on-road and non-road air borne manganese concentrations. Median income by county was inversely associated with chronic liver disease mortality, while the logarithmically transformed airborne concentrations of on-road manganese were positively correlated with county-level chronic liver disease mortality. Because environmental manganese near roads is likely to increase over time, these pilot findings potentially have regulatory implications and argue for further research.
机译：锰是必需的微量元素，在高剂量时有毒。在过去的几十年中，锰已取代铅作为汽油中的抗爆剂，引起人们对该元素对空气和路边污染的关注。另外，锰被肝脏吸收，使特定人群（例如孕妇，婴儿和儿童以及患有肝病的患者）易受其毒性作用。这项生态研究利用美国人口普查局，北卡罗来纳州健康统计中心和美国环境保护局的数据，评估了北卡罗来纳州100个县的慢性肝病死亡率。它将这些比率与县级人口统计数据以及公路和非公路上空气传播的锰浓度相关联。县的中位数收入与慢性肝病死亡率呈负相关，而对数转换后的空气中道路锰浓度与县级慢性肝病死亡率呈正相关。由于道路附近环境锰的含量可能会随着时间的推移而增加，因此这些试验性发现可能会对法规产生影响，并要求进一步研究。

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