...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>International Journal of General Medicine >Clinical features of spontaneous hypothyroidism in one physician’s practice in Jamaica
【24h】

Clinical features of spontaneous hypothyroidism in one physician’s practice in Jamaica

机译：牙买加一名医师的实践中自发性甲状腺功能减退的临床特征

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Objective: To describe the clinical characteristics of patients with spontaneous hypothyroidism, the frequency of chronic autoimmune thyroiditis, and the thyroid autoantibody most often associated with this condition in a referral population in Jamaica.Methods: A retrospective study of all cases referred to the author’s endocrinology practice from 1995 to 2005 with a diagnosis of spontaneous hypothyroidism was undertaken. The clinical history, examination findings, biochemical test results, thyroid autoimmune antibodies, and imaging data were reviewed.Results: Spontaneous primary hypothyroidism was correctly diagnosed in 53 subjects. Fifty of the patients were females and three were males. Mean age was 43.3 years (range 12–82 years); 24.4% of the patients had a family member with thyroid disease; 27.1% presented because of a goiter; and 54.2% because of symptoms suggestive of hypothyroidism. The thyroid was palpable in 56.3% and thyroid ultrasound was consistent with Hashimoto’s thyroiditis on 64% of occasions. Only 8% of the patients had the atrophic variant of hypothyroidism. Antithyroid peroxidase and antithyroglobulin antibody were positive in 75.8% and 37.5% of patients, respectively. Chronic autoimmune thyroiditis was confirmed in 78.8% of cases.Conclusion: In these cases in Jamaica, spontaneous hypothyroidism was predominantly a female disorder. Chronic autoimmune thyroiditis was the commonest cause, and antithyroid peroxidase antibody was the thyroid antibody most likely to be positive in this population.
机译：目的：描述在牙买加转诊人群中自发性甲状腺功能减退症患者的临床特征，慢性自身免疫性甲状腺炎的发生频率以及与这种情况最常相关的甲状腺自身抗体。方法：所有涉及作者内分泌学的病例的回顾性研究从1995年至2005年进行了诊断为自发性甲状腺功能减退症的治疗。回顾了其临床病史，检查结果，生化检查结果，甲状腺自身免疫抗体和影像学数据。结果：53例受试者均被正确诊断为自发性原发性甲状腺功能减退症。患者中有五十名是女性，三名是男性。平均年龄为43.3岁（范围12-82岁）; 24.4％的患者患有甲状腺疾病的家庭成员;由于甲状腺肿而占27.1％;和54.2％是由于甲状腺功能减退的症状所致。甲状腺可触及率为56.3％，甲状腺超声与桥本氏甲状腺炎相符的情况为64％。仅有8％的患者患有萎缩性甲状腺功能减退症。抗甲状腺过氧化物酶和抗甲状腺球蛋白抗体分别在75.8％和37.5％的患者中呈阳性。确诊为慢性自身免疫性甲状腺炎的病例为78.8％。结论：在牙买加的这些病例中，自发性甲状腺功能减退症主要是女性疾病。慢性自身免疫性甲状腺炎是最常见的原因，而抗甲状腺过氧化物酶抗体是该人群中最有可能阳性的甲状腺抗体。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号