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首页> 外文期刊>International Journal of Chronic Diseases >Mean Platelet Volume and Splenomegaly as Useful Markers of Subclinical Activity in Egyptian Children with Familial Mediterranean Fever: A Cross-Sectional Study
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Mean Platelet Volume and Splenomegaly as Useful Markers of Subclinical Activity in Egyptian Children with Familial Mediterranean Fever: A Cross-Sectional Study

机译：平均血小板量和脾肿大作为埃及家族性地中海热儿童的亚临床活性的有用标志物：一项跨领域研究

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Objective. To study whether mean platelet volume (MPV) and splenomegaly could be used as subclinical inflammatory markers in children with familial Mediterranean fever (FMF) at the attack-free period.Patients and Methods. The study included ninety-seven children with FMF. MPV was carried out within 4 hours of blood sampling according to standard laboratory practice. Splenomegaly was determined by abdominal ultrasound (USG).Results. High MPV was detected in 84.45% of our studied patients and was significantly higher in FMF patients with splenomegaly than in patients without splenomegaly. There was a statistically significant correlation between MPV and splenic span (P=0.045).Conclusion. Elevated MPV and its significant correlation with splenic span in FMF children during the attack-free periods support the use of MPV and splenomegaly as useful markers of the subclinical inflammation in FMF patients at the attack-free period.
机译：目的。研究在无发作期平均血小板体积（MPV）和脾肿大是否可以用作家族性地中海热（FMF）儿童的亚临床炎症指标。患者和方法。该研究纳入了97名患有FMF的儿童。根据标准实验室操作，在采血后4小时内进行MPV。通过腹部超声（USG）确定脾肿大。在我们研究的患者中检出的MPV较高，占84.45％，在患有脾肿大的FMF患者中明显高于未患有脾肿大的患者。 MPV与脾跨度之间有统计学意义的相关性（P = 0.045）。在无发作期，FMV儿童中MPV升高及其与脾脏跨度的显着相关性支持将MPV和脾肿大作为无发作期FMF患者亚临床炎症的有用标志物。

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