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首页> 外文期刊>International Journal of Hepatology >The Association between Female Genital Cutting and Spousal HCV Infection in Egypt
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The Association between Female Genital Cutting and Spousal HCV Infection in Egypt

机译：埃及女性生殖器切割与配偶HCV感染之间的关联

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Objective. To identify the risk factors for HCV infection within married couples in Egypt.Methods. In 2008 Egypt conducted its first nationally representative survey of HCV prevalence. 11126 of the 12780 individuals aged 15–59 year who were sampled agreed to participate and provided information via a questionnaire about demographic and behavioural characteristics and blood for HCV antibody and RNA analysis. We assessed the risk factors for HCV infection in a subsample of 5182 married individuals via multivariate logistic regression.Results. Overall HCV antibody prevalence in the married couples was 18.2% (95% CI, 16.8–19.6). HCV antibody prevalence was higher in the husbands (23.7%) than the wives (12.1%;P<0.001). Having a spouse who was infected with HCV was an independent risk factor for HCV infection with odds ratios of 2.1 (95% CI, 1.6–2.9) and 2.2 (95% CI, 1.6–3.1) for women and men, respectively. Husbands whose wives had experienced female genital cutting (FGC) had a higher prevalence of HCV and this relationship was driven by a strong association in urban areas. Amongst the women there was no association between FGC and HCV overall but in urban areas only women who had experienced FGC were HCV infected.Conclusions. This study provides additional evidence of the importance of intrafamilial transmission of HCV in Egypt.
机译：目的。目的确定埃及已婚夫妇中HCV感染的危险因素。 2008年，埃及进行了首次全国性的HCV流行率调查。在12780名年龄在15-59岁之间的个体中，有11126名同意参加，并通过问卷提供有关人口统计学和行为特征以及血液的HCV抗体和RNA分析信息。我们通过多元logistic回归评估了5182名已婚个体的子样本中HCV感染的危险因素。已婚夫妇的总体HCV抗体患病率为18.2％（95％CI，16.8-19.6）。丈夫中的HCV抗体患病率（23.7％）高于妻子（12.1％; P <0.001）。拥有HCV感染的配偶是HCV感染的独立危险因素，男女的比值比分别为2.1（95％CI，1.6-2.9）和2.2（95％CI，1.6-3.1）。妻子的妻子经历过女性生殖器切割（FGC）的丈夫中HCV的患病率较高，而这种关系是由城市地区的强大联系所驱动的。在这些妇女中，FGC和HCV总体上没有关联，但是在城市地区，只有经历过FGC的妇女才感染HCV。这项研究提供了另外的证据，证明埃及家庭中传播HCV的重要性。

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