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首页> 外文期刊>International Journal of Infection Control >Skin compatibility of two ethanol based virucidal hand disinfectants
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Skin compatibility of two ethanol based virucidal hand disinfectants

机译：两种乙醇基杀菌手消毒剂的皮肤相容性

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Two virucidal hand rubs containing high concentrations of ethanol were evaluated for their irritating and sensitizing propensities in a Human Repeated Insult Patch Test (HRIPT). Whereas the numbers of responses elicited by Product A and an ethanol control were commensurately low and not significantly different (p<0.256), the number elicited by Product B was significantly higher than those elicited by either Product A or control (p<0.001). Product A was found to be devoid of clinically significant irritating propensities; Product B, a weak cumulative irritant. It was shown that it is possible to use high concentrations of ethanol in formulating highly effective virucidal hand disinfectants without compromising the skin compatibility of the product.
机译：在人类重复伤害斑贴试验（HRIPT）中，评估了两种含高浓度乙醇的杀手性手膏的刺激性和致敏性。尽管产品A和乙醇对照组引起的应答数量相当低且无显着差异（p <0.256），但产品B引起的应答数量显着高于产品A或对照组引起的应答数量（p <0.001）。发现产品A没有临床上明显的刺激性。产品B，累积刺激性弱。结果表明，在配制高效杀手手消毒剂时，可以使用高浓度的乙醇，而不会损害产品的皮肤相容性。

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