...
首页> 外文期刊>International Journal of Hematological Disorders >Effect of G6pd Status in Malaria Infected Individuals on Cortisol, Malondialdehyde, Blood Glucose and Blood Lipid Profile
【24h】

Effect of G6pd Status in Malaria Infected Individuals on Cortisol, Malondialdehyde, Blood Glucose and Blood Lipid Profile

机译:疟疾感染者体内G6pd状况对皮质醇,丙二醛,血糖和血脂谱的影响

获取原文
           

摘要

The aim of this study was to determine the effect of Glucose-6-Phosphate dehydrogenase (G6PD) status in Plasmodium falciparum malaria infected individuals cortisol, malondialdehyde (MDA), blood glucose and blood lipid profile. The study was conducted at Federal Medical Centre, Ido-Ekiti, Nigeria. Two hundred and two blood samples were collected twice from each malaria infected individuals. Thick blood film was made and stained with Giemsa’s staining technique for malaria parasite detection; Glucose-6-Phosphate dehydrogenase (G-6-PD) was performed using methaemoglobin reduction method. Data obtained was analysed using SPSS version 16. The result of this present study showed that the mean±SD of cortisol and malondialdehyde (MDA) in G6PD normal were higher compared to G6PD deficient in pre and post anti-malaria drug treatment. Cortisol levels increased in patients with P.falciparum malaria infection, which decline as the clinical condition improved and parasitaemia decrease during anti malaria treatment.
机译:这项研究的目的是确定葡萄糖-6磷酸脱氢酶(G6PD)状态对恶性疟原虫疟疾感染者的皮质醇,丙二醛(MDA),血糖和血脂谱的影响。这项研究是在尼日利亚伊多埃基蒂的联邦医疗中心进行的。从每个疟疾感染者中两次采集了222个血液样本。制作了厚厚的血膜,并用Giemsa的染色技术进行了染色以检测疟原虫。使用甲基血红蛋白还原法进行葡萄糖6-磷酸脱氢酶(G-6-PD)。使用SPSS 16版对获得的数据进行了分析。本研究的结果表明,与抗疟疾药物治疗前后的G6PD缺乏相比,G6PD正常者的皮质醇和丙二醛(MDA)的平均值±SD更高。恶性疟原虫疟疾感染患者的皮质醇水平升高,随着抗疟疾治疗期间临床状况的改善和寄生虫血症的减少,皮质醇水平下降。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号