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首页> 外文期刊>International journal of molecular imaging >SPECT/CT for Lymphatic Mapping of Sentinel Nodes in Early Squamous Cell Carcinoma of the Oral Cavity and Oropharynx
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SPECT/CT for Lymphatic Mapping of Sentinel Nodes in Early Squamous Cell Carcinoma of the Oral Cavity and Oropharynx

机译：SPECT / CT用于口腔和口咽早期鳞状细胞癌前哨淋巴结的淋巴定位

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Adequate staging and treatment of the neck in squamous cell carcinoma of the oral cavity and oropharynx (OSCC) is of paramount importance. Elective neck dissection (END) of the clinical N0-neck is widely advocated as neck treatment. With regard to the prevalence of 20–40% of occult neck metastases found in the ND specimens, the majority of patients undergo surgery of the lymphatic drainage basin without therapeutic benefit. Sentinel node biopsy (SNB) has been shown to be a safe, reliable and accurate alternative treatment modality for selected patients. Using this technique, lymphatic mapping is crucial. Previous reports suggested a benefit of single photon emission computed tomography with CT (SPECT/CT) over dynamic planar lymphoscintigraphy (LS) alone. SPECT/CT allows the surgeon for better topographical orientation and delineation of sentinel lymph nodes (SLN’s) against surrounding structures. Additionally, SPECT/CT has the potential to detect more SLN’s which might harbour occult disease, than LS. SPECT/CT is recommended to be used routinely, although SPECT/CT is not indispensable for successful SNB.
机译：口腔鳞状细胞癌和口咽癌（OSCC）的充分分期和颈部治疗至关重要。临床N0颈的择期颈清扫术（END）被广泛提倡为颈部治疗。关于在ND标本中发现的20％至40％的隐匿性颈部转移的患病率，大多数患者接受了淋巴引流盆的手术而没有治疗益处。前哨淋巴结活检（SNB）已被证明是针对特定患者的安全，可靠和准确的替代治疗方式。使用这种技术，淋巴标测至关重要。先前的报道表明，单光子发射计算机断层扫描（CT）（SPECT / CT）优于单独的动态平面淋巴细胞闪烁成像（LS）。 SPECT / CT使外科医生可以更好地进行地形定位，并确定前哨淋巴结（SLN）对周围结构的轮廓。此外，与LS相比，SPECT / CT更有可能检测出更多可能带有隐匿性疾病的SLN。尽管SPECT / CT对于成功的SNB并非必不可少，但建议常规使用SPECT / CT。

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