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首页> 外文期刊>International journal of molecular imaging >FDG-PET or PET/CT in Fever of Unknown Origin: The Diagnostic Role of Underlying Primary Disease
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FDG-PET or PET/CT in Fever of Unknown Origin: The Diagnostic Role of Underlying Primary Disease

机译：FDG-PET或PET / CT在未知来源的热中：基础原发性疾病的诊断作用

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Fever of unknown origin (FUO) is generally defined as a fever greater than 38.3°C on several occasions during a period longer than 3 weeks for which the etiology behind cannot be diagnosed at the end of at least 1 week hospital stay. Conventional diagnostic methods are still not adequate to reveal underlying reason in approximately 50% of patients with FUO. In patients with certain diagnosis, three major categories are infections, malignancies, and noninfectious inflammatory diseases. Fluoro-18-fluoro-2-deoxy-D-glucose (FDG) is a structural analog of 2-deoxyglucose and accumulates in malignant tissues but also at sites of infection and inflammation. For this reason, FDG PET or PET/CT has great advantage in understanding of underlying pathology in assessment of FUO. However, till today, there are limited studies about the role of FDG PET or PET/CT in evaluation of FUO. In this paper, the impact of FDG PET or PET/CT in the diagnostic work-up of FUO is described by data obtained from literature review.
机译：来历不明的发热（FUO）通常被定义为在超过3周的时间内，有几次发烧超过38.3°C，而在住院至少1周后仍无法诊断出其病因。常规诊断方法仍不足以揭示大约50％的FUO患者的根本原因。在具有特定诊断的患者中，三大类是感染，恶性肿瘤和非感染性炎性疾病。氟-18-氟-2-脱氧-D-葡萄糖（FDG）是2-脱氧葡萄糖的结构类似物，在恶性组织中积累，在感染和炎症部位也积累。因此，FDG PET或PET / CT在了解FUO评估的潜在病理方面具有很大优势。但是，直到今天，有关FDG PET或PET / CT在FUO评估中的作用的研究还很有限。本文通过文献综述获得的数据描述了FDG PET或PET / CT对FUO诊断的影响。

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