Parametric Images in Assessing Bone Grafts Using Dynamic18F-Fluoride PET

LingfengWen; StefanEberl; (David) DaganFeng; PaulStalley; GangHuang; Michael J.Fulham

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Parametric Images in Assessing Bone Grafts Using Dynamic18F-Fluoride PET

机译：使用Dynamic18F-Fluoride PET评估骨移植物中的参数化图像

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The early identification of graft failure would improve patient management.18F-fluoride is a suitable tracer for quantifying bone metabolism. Performance of parametric images constructed by Patlak graphical analysis (PGA) with various time periods was evaluated in the analysis of dynamic18F-fluoride PET studies of eight patients with fibula bone grafts after limb salvage surgery. The PGA parametric image approach tended to underestimate influx rate. The linear portion of PGA analysis was found to be from 10 to 50 min. It shows promise in providing a quantitative assessment of the viability of bone grafts.

机译：尽早发现移植物衰竭将改善患者管理。18 F-氟化物是定量骨代谢的合适示踪剂。通过对八名肢体抢救手术后腓骨植骨患者的动态18 F-氟化物PET分析，评估了通过Patlak图形分析（PGA）构造的参数图像在不同时间段的性能。 PGA参数图像方法往往会低估流入率。发现PGA分析的线性部分为10至50µmin。它显示了对骨移植物的可行性进行定量评估的希望。

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《International journal of molecular imaging》 |2011年第5期|共8页
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LingfengWen; StefanEberl; (David) DaganFeng; PaulStalley; GangHuang; Michael J.Fulham;
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Parametric Images in Assessing Bone Grafts Using Dynamic18F-Fluoride PET

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