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首页> 外文期刊>International Journal of Nephrology >Mortality in Patients on Renal Replacement Therapy and Permanent Cardiac Pacemakers
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Mortality in Patients on Renal Replacement Therapy and Permanent Cardiac Pacemakers

机译：肾脏替代治疗和永久性心脏起搏器的患者死亡率

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摘要

End stage renal disease is a relatively frequent disease with high mortality due to cardiac causes. Permanent pacemaker (PM) implantation rates are also very common; thus combination of both conditions is not unusual. We hypothesized that patients with chronic kidney disease with a PM would have significantly higher mortality rates compared with end stage renal disease patients without PM. Our objectives were to analyze mortality of patients on renal replacement therapy with PM. 2778 patients were on renal replacement therapy (RRT) and 110 had a PM implanted during the study period. To reduce the confounding effects of covariates, a propensity-matched score was performed. 52 PM patients and 208 non-PM matched patients were compared. 41% of the PM were implanted before entering the RRT program and 59% while on RRT. Mortality was higher in the PM group. Cardiovascular disease and infections were the most frequent causes of death. Propensity analysis showed no differences in long-term mortality between groups. We concluded that in patients on RRT and PM mortality rates are higher. Survival curves did not differ from a RRT propensity-matched group. We concluded that the presence of a PM is not an independent mortality risk factor in RRT patients.
机译：终末期肾脏疾病是一种相对常见的疾病，由于心脏原因而导致高死亡率。永久性起搏器（PM）植入率也很常见。因此，两种情况的结合并不罕见。我们假设与没有PM的终末期肾病患者相比，患有PM的慢性肾脏病患者的死亡率要高得多。我们的目标是分析接受PM肾替代疗法的患者的死亡率。在研究期间，有2778例患者接受了肾脏替代治疗（RRT），其中110例植入了PM。为了减少协变量的混杂效应，进行了倾向匹配得分。比较52例PM患者和208例非PM匹配患者。进入RRT计划之前，有41％的PM被植入，而进入RRT时则有59％。 PM组的死亡率较高。心血管疾病和感染是最常见的死亡原因。倾向分析显示两组之间的长期死亡率无差异。我们得出的结论是，接受RRT和PM的患者死亡率较高。生存曲线与RRT倾向匹配组无差异。我们得出结论，在RRT患者中，PM的存在不是独立的死亡危险因素。

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